P5555
葛根素
analytical standard
别名:
8-(β-D-吡喃葡萄糖基-7-羟基-3-(4-羟基苯基)-4H-1-苯并吡喃-4-酮, 葛根素
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关于此项目
经验公式（希尔记法）:
C21H20O9
化学文摘社编号:
分子量:
416.38
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
64198
产品名称
葛根素, analytical standard
InChI
1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)ccc3C(=O)C(=COc23)c4ccc(O)cc4
InChI key
HKEAFJYKMMKDOR-VPRICQMDSA-N
grade
analytical standard
assay
~80% (HPLC)
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
forensics and toxicology
veterinary
format
neat
Quality Level
Gene Information
mouse ... Aldh1a2(19378), Maoa(17161)
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Application
有关合适仪器技术的更多信息，请参考产品′s分析证书。如需进一步支持，请联系技术服务。
葛根素可用作参考标准品，用于通过高效液相色谱法（HPLC）检测葛根异黄酮给药后大鼠血浆中的葛根素浓度。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Lei Wang et al.
PloS one, 14(6), e0218490-e0218490 (2019-06-25)
Growing evidence indicates that the gut microbiota plays a significant role in the pathophysiological processes of obesity and its related metabolic symptoms in the host. Puerarin, an active ingredient in the root of Pueraria lobate has been suggested to have
HPLC method for the determination and pharmacokinetic studies on puerarin in cerebral ischemia reperfusion rat plasma after intravenous administration of puerariae radix isoflavone
Yan B, et al.
Journal of Pharmaceutical and Biomedical Analysis, 37(2), 297-301 (2005)
Rong Li et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 52, 69-75 (2012-11-14)
This study was designed to evaluate the potential effects of puerarin (PR), an effective isoflavonoid compound purified from Pueraria lobata, in treating hepatic fibrosis (HF) rats induced by carbon tetrachloride (CCl(4), 2 mL kg(-1) d(-1)). Compared to model control, PR
Y Zou et al.
Free radical research, 47(1), 55-63 (2012-10-24)
Current evidence suggests that amyloid beta (Aβ) peptides may play a major role in the pathogenesis of Alzheimer's disease in part by eliciting oxidative stress. Puerarin, a major isoflavone glycoside from Kudzu root (Pueraria lobata), has been reported to exert
Rong Li et al.
International immunopharmacology, 17(1), 71-78 (2013-06-12)
Puerarin (PR) has been utilized as a phytomedicine to managing liver disease in China. Thus, this study aimed to evaluate the potential PR-mediated hepatoprotective role against chronic alcohol-induced liver injury in rats. The results indicated that serum levels of alanine
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