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Merck
CN

P8074

TWEEN ® 80

BioXtra, viscous liquid

别名:

吐温80(TWEEN® 80), POE (20)山梨糖醇酐单油酸酯, 聚乙二醇山梨醇酐单油酸酯, 聚山梨酯 80, 聚氧乙烯山梨糖醇酐单油酸酯

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化学文摘社编号:
9005-65-6
UNSPSC Code:
12161900
NACRES:
NA.21
MDL number:
MFCD00082107

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产品名称

TWEEN ® 80, BioXtra, viscous liquid

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

description

non-ionic

product line

BioXtra

form

viscous liquid

mol wt

micellar avg mol wt 79,000
average mol wt 1310

composition

Oleic acid, ~70% (balance primarily linoleic, palmitic, and stearic acids)

aggregation number

60

technique(s)

DNA extraction: suitable
RNA extraction: suitable
cell culture | mammalian: suitable
protein purification: suitable

impurities

≤0.025% Phosphorus (P)

ign. residue

<0.1%

CMC

0.012 mM (20-25°C)

transition temp

cloud point 65 °C

density

1.06 g/mL at 25 °C

anion traces

chloride (Cl-): <0.05%
sulfate (SO42-): <0.05%

cation traces

Al: <0.0005%
Ca: <0.001%
Cu: <0.0005%
Fe: <0.0005%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Na: <0.05%
Pb: <0.001%
Zn: <0.0005%

HLB

15

Quality Level

200

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相关类别

Application

[“TWEEN”]80 已用于：
  • 溶解雷帕霉素（RAPA）,以进行免疫抑制处理，进行小鼠体内研究
  • 溶解重塑蛋白和重塑蛋白 Fluor，评估重塑蛋白在体内和小分子给药中的毒性
  • 制备用于总叶酸微生物测定的测定介质

General description

[“TWEEN”]80 是一种聚乙烯山梨醇酯，广泛用于生物化学应用，如溶解蛋白质、从培养细胞中分离细胞核和培养结核杆菌。它还可用于乳化和分散医药和食品中的物质。TWEEN 80 在冰淇淋中起到了活性干燥剂的作用。

Legal Information

TWEEN is a registered trademark of Croda International PLC

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN2107
BCCL8873
BCCJ7552
BCCH2519
BCCF5441

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Workflow for the Analysis of Polysorbate 80 in Erbitux® Formulation

A complete reversed phase HPLC-ELSD workflow, including sample preparation for the analysis of Polysorbate 80 in a monoclonal antibody formulation.

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