P9755
吡哆醇 盐酸盐
≥98% (HPLC)
别名:
吡哆醇盐酸盐, PN HCl, 吡哆醇 盐酸盐, 抗皮炎素 盐酸盐, 维生素 B6 盐酸盐
质量水平
方案
≥98% (HPLC)
表单
powder
技术
HPLC: suitable
颜色
white to off-white
mp
214-215 °C (lit.)
SMILES字符串
Cl[H].Cc1ncc(CO)c(CO)c1O
InChI
1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
InChI key
ZUFQODAHGAHPFQ-UHFFFAOYSA-N
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应用
盐酸吡哆醇已用于：
- 用作基础培养基中的维生素补充剂，培养摩加夫芽胞杆菌(Bacillus mojavensis)和枯草芽孢杆菌(Bacillus subtilis )菌株
- 用作预处理培养基/MS盐中的补充剂，以启动白咖啡(Coffea canephora )种子的体细胞胚胎发生诱导
- 仔猪口服给药，以研究其 对同型半胱氨酸血症进程的影响
生化/生理作用
吡哆醇/维生素 B6 在神经、免疫和内分泌系统中具有关键作用，还参与蛋白质、脂质和碳水化合物的代谢过程。缺乏吡哆醇可能导致抽搐和癫痫性脑病，并导致婴儿畸形。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Marie-Édith Côté-Robitaille et al.
Journal of nutritional science, 4, e31-e31 (2015-10-27)
Homocysteine (Hcy) is an intermediary sulphur amino acid recognised for pro-oxidative properties in several species which may weaken immune competence in piglets. In this species, there is an acute 10-fold increase of concentrations of plasma Hcy (pHcy) during the first
Ilan Matok et al.
Journal of clinical pharmacology, 53(3), 334-338 (2013-02-28)
Although Diclectin (doxylamine/pyridoxine delayed-released combination) is widely used in Canada, its pharmacokinetics (PK) during pregnancy has never been described. The objective of this study was to compare the PK of doxylamine/pyridoxine delayed-released combination in pregnant versus nonpregnant women. The apparent
Sonia Fargue et al.
Biochimica et biophysica acta, 1832(10), 1776-1783 (2013-04-20)
Primary hyperoxaluria type 1 (PH1) is a rare hereditary calcium oxalate kidney stone disease caused by a deficiency of the liver-specific pyridoxal-phosphate-dependent peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT). About one third of patients are responsive to pharmacological doses of pyridoxine (vitamin
Eduard Alexander Struys et al.
Pediatrics, 130(6), e1716-e1719 (2012-11-14)
α-Amino adipic semialdehyde (α-AASA) accumulates in body fluids from patients with pyridoxine-dependent epilepsy because of mutations in antiquitin (ALDH7A1) and serves as the biomarker for this condition. We have recently found that the urinary excretion of α-AASA was also increased
Vijay P Singh et al.
The Journal of organic chemistry, 78(4), 1478-1487 (2013-01-16)
Vitamin B6 is involved in a variety of enzymatic transformations. Some recent findings also indicate an antioxidant role of the vitamin in biological systems. We set out to turn pyridoxine (1a) into a catalytic chain-breaking and hydroperoxide-decomposing antioxidant by replacing
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