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Merck
CN

PHL80491

Lithospermic acid

phyproof® Reference Substance

别名:

Lithospermic acid A

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关于此项目

经验公式(希尔记法):
C27H22O12
化学文摘社编号:
分子量:
538.46
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
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SMILES string

O1C(C(c3c1c(ccc3\C=C\C(=O)O[C@H](Cc4cc(c(cc4)O)O)C(=O)O)O)C(=O)O)c2cc(c(cc2)O)O

InChI

1S/C27H22O12/c28-15-5-1-12(9-18(15)31)10-20(26(34)35)38-21(33)8-4-13-2-7-17(30)25-22(13)23(27(36)37)24(39-25)14-3-6-16(29)19(32)11-14/h1-9,11,20,23-24,28-32H,10H2,(H,34,35)(H,36,37)/b8-4+/t20-,23?,24?/m1/s1

InChI key

UJZQBMQZMKFSRV-UJVFRBSWSA-N

grade

primary reference standard

product line

phyproof® Reference Substance

assay

≥90.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

storage temp.

−20°C

General description

phyproof® reference substances are valuable tools for quality control purposes of herbal raw materials, extracts, finished herbal medicinal products, dietary supplements or food products, for general scientific projects at universities or research organizations, or during screenings for new drug candidates in the pharmaceutical industry.Lithospermic acid (LSA) is isolated from the roots of Salvia mitiorrhiza, a herb used in traditional Chinese medicine. This plant-derived pharmaceutically active component is reported to exhibit various physiological effects.

Application

Lithospermic acid may be used as a reference standard for the determination of the analyte in hairy root cultures of Salvia miltiorrhiza, commercial herbal drugs, and Chinese traditional medicine by different chromatography techniques.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Quantitative analysis of highly similar salvianolic acids with 1H qNMR for quality control of traditional Chinese medicinal preparation Salvianolate Lyophilized Injection
Chen X, et al.
Journal of Pharmaceutical and Biomedical Analysis, 124, 281-287 (2016)
The effect of lithospermic acid, an antioxidant, on development of diabetic retinopathy in spontaneously obese diabetic rats
Jin CJ, et al.
Testing, 9(6), e98232-e98232 (2014)
Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in rats
Liu X, et al.
Chemico-Biological Interactions, 176(2-3), 137-142 (2008)
Determination of polyphenolic compounds in commercial herbal drugs and spices from Lamiaceae: thyme, wild thyme and sweet marjoram by chromatographic techniques
Fecka I and Turek S
Food Chemistry, 108(3), 1039-1053 (2008)
Production of lithospermic acid B and rosmarinic acid in hairy root cultures of Salvia miltiorrhiza
Chen H, et al.
Journal of Industrial Microbiology & Biotechnology, 22(3), 133-138 (1999)

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