Name: 法莫替丁
Brand: SIAL

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About This Item

经验公式（希尔记法）:

C₈H₁₅N₇O₂S₃

CAS Number:

76824-35-6

分子量:

337.45

MDL编号:

MFCD00079297

UNSPSC代码:

41116107

PubChem化学物质编号:

329823085

NACRES:

NA.24

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生物来源

synthetic

质量水平

300

等级

certified reference material
pharmaceutical secondary standard

Agency

BP
EP
USP
traceable to BP 653
traceable to Ph. Eur. F0050000
traceable to USP 1269200

蒸汽压

<0.0000001 kPa ( 25 °C)

API类

famotidine

CofA

current certificate can be downloaded

包装

pkg of 1 g

储存条件

protect from light (20 mm aluminium crimp seal for unused portion)

技术

HPLC: suitable
gas chromatography (GC): suitable

颜色

white to pale yellow-white

mp

325.4-327.2 °F (163—164°C)

溶解性

DMF: freely soluble
acetone: practically insoluble
chloroform: practically insoluble
ethanol: practically insoluble
ether: practically insoluble
ethyl acetate: practically insoluble
glacial acetic acid: freely soluble
methanol: slightly soluble
water: very slightly soluble

应用

pharmaceutical (small molecule)

包装形式

neat

运输

ambient

储存温度

2-8°C

SMILES字符串

N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI

1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)

InChI key

XUFQPHANEAPEMJ-UHFFFAOYSA-N

基因信息

human ... HRH2(3274)

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一般描述

Famotidine is a histamine H2-receptor antagonist, which promotes the healing of erosive esophagitis, gastric and duodenal ulcers since it inhibits the gastric acid secretion in humans.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Famotidine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using different chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

H₂组胺受体拮抗剂；抗溃疡剂。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA7133 in the slot below. This is an example certificate only and may not be the lot that you receive.

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)