PHR1126
磺胺甲噁唑
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
4-氨基- N -（5-甲基-3-异恶唑基）苯磺酰胺, N 1 -（5-甲基异恶唑-3-基）磺胺
等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
USP 1631001
traceable to Ph. Eur. S2100000
API类
sulfamethoxazole
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-30°C
SMILES字符串
Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI
1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
InChI key
JLKIGFTWXXRPMT-UHFFFAOYSA-N
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一般描述
用于 质量控制的认证药物二级标准品为 制药实验室和制造商提供了一种方便且具有成本效益 的主要标准替代品磺胺甲恶唑是用于治疗人类泌尿道感染的最有效的磺胺类药物之一。
应用
磺胺甲恶唑可作为药物参考标准品，通过方波伏安法以及可见光和紫外分光光度技术对药物制剂中的分析物进行测定。
这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
分析说明
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
其他说明
想要查看本品的检验报告示例，请在下框中输入LRAA6910。这只是一个示例证书，可能与您收到的批次不符。
该认证标准物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在检验报告上找到。
警示用语：
Warning
危险声明
危险分类
Aquatic Chronic 2 - Repr. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 2
Determination of sulfamethoxazole and trimethoprim in pharmaceuticals by visible and UV spectrophotometry.
Shamsa F and Amani L
Iranian Journal of Pharmaceutical Research : IJPR, 31-36 (2010)
Electroanalytical determination of sulfadiazine and sulfamethoxazole in pharmaceuticals using a boron-doped diamond electrode.
Souza CD, et al.
Sensors and Actuators B, Chemical, 135(1), 66-73 (2008)
Ming Xie et al.
Water research, 47(13), 4567-4575 (2013-06-15)
The impact of humic acid fouling on the membrane transport of two pharmaceutically active compounds (PhACs) - namely carbamazepine and sulfamethoxazole - in forward osmosis (FO) was investigated. Deposition of humic acid onto the membrane surface was promoted by the
Karl J Schreiber et al.
BMC plant biology, 12, 226-226 (2012-11-28)
The sulfanilamide family comprises a clinically important group of antimicrobial compounds which also display bioactivity in plants. While there is evidence that sulfanilamides inhibit folate biosynthesis in both bacteria and plants, the complete network of plant responses to these compounds
Alexandra G Gonçalves et al.
Journal of hazardous materials, 239-240, 167-174 (2012-09-27)
Two carbon materials (multi-walled carbon nanotubes, MWCNTs, and activated carbon) were investigated as ozonation catalysts for the mineralization of the antibiotic sulphamethoxazole (SMX). MWCNTs presented a higher catalytic performance than activated carbons, which was justified by their differences in surface
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