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Merck
CN

PHR1132

盐酸甲氧氯普胺

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Metoclopramide HCl

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关于此项目

NACRES:
NA.24
UNSPSC Code:
41116107
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产品名称

盐酸甲氧氯普胺, Pharmaceutical Secondary Standard; Certified Reference Material

grade

certified reference material
pharmaceutical secondary standard

agency

USP 1440808
traceable to Ph. Eur. M1825000

API family

metoclopramide

CofA

current certificate can be downloaded

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Metoclopramide Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and biological fluids by chromatography and chemiluminescence techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Metoclopramide Hydrochloride is an antiemetic drug and is generally used for the treatment of gastrointestinal disorders. It can also exhibit sedative, extrapyrimidal, and prolactin secretion stimulation actions.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7152 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

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Rapid liquid chromatographic analysis of metoclopramide in pharmaceutical preparations
Aboul-Enein HY and Islam MR
Toxicological & Environmental Chemistry, 26(1-4), 197-201 (1990)
Flow-injection chemiluminescent determination of metoclopramide hydrochloride in pharmaceutical formulations and biological fluids using the [Ru (dipy) 32+]-permanganate system
Al-Arfaj NA
Talanta, 62(2), 255-263 (2004)
Assessment of a controlled release hydrophilic matrix formulation for metoclopramide HCl
Hasan EI, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 55(3), 339-344 (2003)
Development and validation of stability indicating HPLC method for estimation of metoclopramide hydrochloride from a novel formulation
Shidhaye S, et al.
Journal of Pharmacy Research, 2(2), 290-295 (2009)
Formulation and evaluation of bi-layer tablet of metoclopramide hydrochloride and ibuprofen
Shiyani B, et al.
Aaps Pharmscitech, 9(3), 818-827 (2008)

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