PHR1136
愈创木酚
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
2-甲氧基苯酚, 儿茶酚单甲醚, 邻羟基苯甲醚
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线性分子式:
(CH3O)C6H4OH
化学文摘社编号:
分子量:
124.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-964-7
Beilstein/REAXYS Number:
508112
MDL number:
InChI key
LHGVFZTZFXWLCP-UHFFFAOYSA-N
InChI
1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3
SMILES string
COc1ccccc1O
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0000619, traceable to USP 1300004
vapor density
4.27 (vs air)
vapor pressure
0.11 mmHg ( 25 °C)
API family
guaiacol
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
refractive index
n20/D 1.543 (lit.)
bp
205 °C (lit.)
Quality Level
density
1.129 g/mL at 25 °C (lit.)
application(s)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Guaiacol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC) and electroanalytical techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
愈创木酚和2，4，6-三氯苯甲醚是造成葡萄酒软木污染的原因。已经开发了一种用于提取和定量两种化合物的方法。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB3328 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
flash_point_f
194.0 °F - closed cup
flash_point_c
90 °C - closed cup
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Garrido JMPJ, et al.
Analytical Letters, 35(15), 2487-2498 (2002)
Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup.
Grosa G, et al.
Journal of Pharmaceutical and Biomedical Analysis, 41(3), 798-803 (2006)
Joel D Mainland et al.
Nature neuroscience, 17(1), 114-120 (2013-12-10)
Humans have ~400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how often genetic polymorphisms in odorant receptors alter receptor function.
Chien-Yun Hsiang et al.
Food chemistry, 136(1), 170-177 (2012-09-29)
Ginger is a commonly used spice with anti-inflammatory potential. Colitis is the common pathological lesion of inflammatory bowel diseases. In this study, we investigated the therapeutic effects of ginger and its component zingerone in mice with 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced
K M Pruitt et al.
Analytical biochemistry, 191(2), 278-286 (1990-12-01)
Because of the important biological functions of peroxidases, there is growing interest in the measurement of their concentrations in various secretions. At present, there is no standard method which allows for comparisons in reported activities. This report describes procedures which
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