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Merck
CN

PHR1244

Supelco

林丹

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

γ-BHC, 1α,2α,3β,4α,5α,6β-六氯环己烷

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关于此项目

经验公式（希尔记法）:
C6H6Cl6
化学文摘社编号:
58-89-9
分子量:
290.83
Beilstein:
1907337
EC 号:
200-401-2
MDL编号:
MFCD00135947
UNSPSC代码:
41116107
PubChem化学物质编号:
329823248
NACRES:
NA.24

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等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to USP 1367504

API类

lindane

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

113-115 °C (lit.)

应用

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

SMILES字符串

Cl[C@H]1[C@H](Cl)[C@H](Cl)[C@@H](Cl)[C@H](Cl)[C@@H]1Cl

InChI

1S/C6H6Cl6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H/t1-,2-,3-,4+,5+,6+

InChI key

JLYXXMFPNIAWKQ-GNIYUCBRSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Lindane is an organochlorine chemical, widely used as an agricultural insecticide and it also finds applications for the pharmaceutical treatment of infestations of lice and scabies.

应用

Lindane may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using gas chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9048 in the slot below. This is an example certificate only and may not be the lot that you receive.

警示用语：

Danger

危险分类

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Lact. - STOT RE 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品
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Simultaneous Determination by Gas Chromatography of Lindane and Carbaryl in Combined Formulations
Sen I, et al.
Journal of Chemistry, 8(1), 391-399 (2011)
John Vijgen et al.
Environmental science and pollution research international, 18(2), 152-162 (2010-11-26)
Hexachlorocyclohexane (HCH) isomers (α-, β- and γ- (Lindane)) were recently included as new persistent organic pollutants (POPs) in the Stockholm Convention, and therefore, the legacy of HCH and Lindane production became a contemporary topic of global relevance. This article wants
Yuji Nagata et al.
Applied microbiology and biotechnology, 76(4), 741-752 (2007-07-20)
gamma-Hexachlorocyclohexane (gamma-HCH, also called gamma-BHC and lindane) is a halogenated organic insecticide that causes serious environmental problems. The aerobic degradation pathway of gamma-HCH was extensively revealed in bacterial strain Sphingobium japonicum (formerly Sphingomonas paucimobilis) UT26. gamma-HCH is transformed to 2,5-dichlorohydroquinone
Microbial degradation of the pesticide lindane (gamma-hexachlorocyclohexane).
B K Singh et al.
Advances in applied microbiology, 47, 269-298 (2003-07-25)
S E Aks et al.
Annals of emergency medicine, 26(5), 647-651 (1995-11-01)
Lindane toxicity has been reported to occur mostly by way of dermal exposure. Cases of ingestion in which blood levels have been determined are rare. We present three such cases, along with a comparison of cases in the literature with
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