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Merck
CN

PHR1346

二甲基砜

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

二甲基砜, 甲基砜

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关于此项目

线性分子式:
(CH3)2SO2
化学文摘社编号:
分子量:
94.13
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-665-9
Beilstein/REAXYS Number:
1737717
MDL number:
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产品名称

二甲基砜, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C2H6O2S/c1-5(2,3)4/h1-2H3

InChI key

HHVIBTZHLRERCL-UHFFFAOYSA-N

SMILES string

CS(C)(=O)=O

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1437600

API family

methylsulfonylmethane

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

238 °C (lit.)

mp

107-109 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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Application

这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

General description

用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
甲基磺酰甲烷是二甲基亚砜的氧化形式,通常存在于绿色植物、水果和蔬菜中。甲基磺酰甲烷可用作溶解多种溶质的溶剂,通常也用于高温反应。它具有药理特性,据报道可减轻外周疼痛、炎症和关节炎状况。

Other Notes

想要查看本品的检验报告示例,请在下框中输入LRAC3469。这只是一个示例证书,可能与您收到的批次不符。
该认证标准物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在检验报告上找到。

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

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Meta-analysis of the related nutritional supplements dimethyl sulfoxide and methylsulfonylmethane in the treatment of osteoarthritis of the knee
Brien S, et al.
Evidence-Based Complementary and Alternative Medicine (2011)
Methylsulfonylmethane (MSM). Monograph.
Alternative medicine review : a journal of clinical therapeutic, 8(4), 438-441 (2003-12-05)
Jacob F Smith et al.
Frontiers in physiology, 11, 80-80 (2020-03-07)
Osteoarthritis (OA) is a degenerative joint disease characterized by inflammatory degradation of articular cartilage and subchondral bone. Wogonin, a compound extracted from the plant Scutellaria baicalensis (colloquially known as skullcap), has previously been shown to have direct anti-inflammatory and antioxidative
S Brien et al.
Osteoarthritis and cartilage, 16(11), 1277-1288 (2008-04-18)
Conventional treatment of osteoarthritis (OA) with non-steroidal anti-inflammatory drugs is associated with serious gastrointestinal side effects and in view of the recent withdrawal of some cyclo-oxygenase-2 inhibitors, identifying safer alternative treatment options is needed. The objective of this systematic review
Youn Hee Joung et al.
International journal of oncology, 44(3), 883-895 (2014-01-10)
Human urinary bladder cancer is the fifth most common cancer, with a worldwide estimate of about two million patients. Recurrence after complete transurethral prostatic resection is the most important problem in therapy. Combination therapy is a new approach in the

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