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Merck
CN

PHR1414

硬脂酸甲酯

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

硬脂酸甲酯, Stearic acid methyl ester, 十八酸甲酯

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关于此项目

线性分子式:
CH3(CH2)16CO2CH3
化学文摘社编号:
分子量:
298.50
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-990-4
Beilstein/REAXYS Number:
1786213
MDL number:
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产品名称

硬脂酸甲酯, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

HPEUJPJOZXNMSJ-UHFFFAOYSA-N

InChI

1S/C19H38O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19(20)21-2/h3-18H2,1-2H3

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OC

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. M1770200
traceable to USP 1437508

API family

methyl stearate

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

181-182 °C/4 mmHg (lit.)

mp

37-41 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Methyl Stearate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by gas-chromatography (GC) coupled to flame-ionization detector (FID).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Methyl stearate is a saturated methyl ester and a representative key molecule of biodiesel fatty acid methyl esters (FAMEs) produced from vegetable oils. It occurs naturally in clove oil.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
To see an example of a Certificate of Analysis for this material enter LRAC1964 in the slot below. This is an example certificate only and may not be the lot that you receive.

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

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Methyl Stearate
USP42-NF37
United States Pharmacopeia/National Formulary, 6180-6180 (2013)
Christophe Capallere et al.
Toxicology in vitro : an international journal published in association with BIBRA, 53, 45-56 (2018-07-28)
In recent years, in vitro skin models combining cell biology and tissue engineering have been developed in order to replace animal models for toxicological studies and to serve as research support to better understand skin biology. This study reports the

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