PHR1459
氯己定
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
氯己定 二盐酸盐, 1,6-双(N5-[对氯苯基]-N1-双胍)己烷；1,1′-己基双(5-[对氯苯基]双胍), 洗必泰
等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to Ph. Eur. C1540000
traceable to USP 1111103
API类
chlorhexidine
CofA
current certificate can be downloaded
包装
pkg of 500 mg
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
Cl.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1
InChI
1S/C22H30Cl2N10.2ClH/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;;/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H
InChI key
WJLVQTJZDCGNJN-UHFFFAOYSA-N
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一般描述
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
应用
Chlorhexidine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in ointment and pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3007 in the slot below. This is an example certificate only and may not be the lot that you receive.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Simultaneous determination of ingredients in an ointment by hydrophobic interaction electrokinetic chromatography.
Okamoto H, et al.
Journal of Chromatography A, 929(1-2), 133-141 (2001)
Chromatography of crotamiton and its application to the determination of active ingredients in ointments.
Izumoto SI, et al.
Journal of Pharmaceutical and Biomedical Analysis, 15(9-10), 1457-1466 (1997)
Quality Standard research of content determination in Compound Chlorhexidine and Dexamethasone Pellicles [J].
ZHANG B, et al.
Northwest Medicine, 6(9-10), 1457-1466 (2011)
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