PHR1578
三乙醇胺
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
2,2′,2′′-次氮基三乙醇, 三(2-羟乙基)胺
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线性分子式:
(HOCH2CH2)3N
化学文摘社编号:
分子量:
149.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-049-8
Beilstein/REAXYS Number:
1699263
MDL number:
InChI
1S/C6H15NO3/c8-4-1-7(2-5-9)3-6-10/h8-10H,1-6H2
InChI key
GSEJCLTVZPLZKY-UHFFFAOYSA-N
SMILES string
OCCN(CCO)CCO
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. T2545000, traceable to USP 1696958
vapor density
5.14 (vs air)
vapor pressure
0.01 mmHg ( 20 °C)
API family
trolamine
CofA
current certificate can be downloaded
autoignition temp.
600 °F
expl. lim.
8.5 %
packaging
ampule of 5 mL
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
Quality Level
useful pH range
7.3-8.3
pKa (25 °C)
7.8
bp
190-193 °C/5 mmHg (lit.)
mp
17.9-21 °C (lit.)
density
1.124 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
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General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standard. Trolamine belongs to the family of ethanolamines, offering a broad spectrum of applications due to its ability to combine the properties of both amines and alcohols. Its property as an organic base to form soluble neutralization products with insoluble acids is reported.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2885 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
354.2 °F - closed cup
flash_point_c
179 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
Toxicology of Mono-, Di-, and Triethanolamine
Knaak BJ, et al.
Reviews of Environmental Contamination and Toxicology, 1-86 (1997)
The Preparation of Emulsions and Other Products with Triethanolamine N(C2H4OH)3, 1-86 (1933)
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