Quality Level
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0001539
API family
pemetrexed
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
[Na+].[Na+].[nH]1c2[nH]cc(c2[c](nc1N)=O)CCc3ccc(cc3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.O.O
InChI
1S/C20H21N5O6.2Na.7H2O/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;;;;;;;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29);;;7*1H2/q;2*+1;;;;;;;/p-2/t13-;;;;;;;;;/m0........./s1
InChI key
QJVSMHJWAOSBMD-MYXYZBIASA-L
General description
培美曲塞是一种治疗指数窄的阴离子抗癌药。作为叶酸抗代谢物，它可用作胸苷酸合成酶的抑制剂。在临床试验中，它可以有效地对抗广谱的实体瘤，例如非小细胞肺癌和乳腺癌。它对二氢叶酸还原酶和甘氨酰胺核糖核苷酸甲酰基转移酶也有效。
Application
Analysis Note
Other Notes
signalword
Danger
hcodes
Hazard Classifications
Muta. 2 - Repr. 1A - Skin Irrit. 2 - STOT RE 1
target_organs
Blood,Immune system,Testes
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| PHR1596-500MG | 04061834431596 |