PHR1660
吲达帕胺
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
吲达帕胺, N-(2-甲基-2,3-二氢-1H-吲哚基)-3-氨磺酰基-4-氯-苯甲酰胺
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关于此项目
经验公式（希尔记法）:
C16H16ClN3O3S
化学文摘社编号:
分子量:
365.83
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
248-012-7
MDL number:
InChI
1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)
InChI key
NDDAHWYSQHTHNT-UHFFFAOYSA-N
SMILES string
CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(N)(=O)=O
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. I0150000, traceable to USP 1338801
API family
indapamide
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
Gene Information
human ... SLC12A3(6559)
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Indapamide is a diuretic that is categorized under the family of benzothiadiazines compounds. It is an oral drug that is usually prescribed as an antihypertensive agent for patients with mild to moderate hypertension.
Indapamide is a diuretic that is categorized under the family of benzothiadiazines compounds. It is an oral drug that is usually prescribed as an antihypertensive agent for patients with mild to moderate hypertension.
Application
Indapamide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques and spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
signalword
Warning
hcodes
Hazard Classifications
Lact. - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Quantitative determination of indapamide in pharmaceuticals and urine by high-performance liquid chromatography with amperometric detection.
Legorburu MJ, et al.
Journal of Chromatographic Science, 37(8), 283-287 (1999)
Determination of certain drugs in binary mixtures formulations by second derivative ratio spectrophotometry and LC.
El-Gindy A, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 59(9), 703-712 (2004)
Development of new spectrophotometric methods for the determination of Indapamide in bulk and Pharmaceutical formulations.
Pai JB, et al.
International Journal of ChemTech Research, 3(2), 755-760 (2011)
Comparison of spectrophotometric and an LC method for the determination perindopril and indapamide in pharmaceutical formulations.
Erk N
Journal of Pharmaceutical and Biomedical Analysis, 26(1), 43-52 (2001)
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