跳转至内容
Merck
CN

PHR1777

奥芬那君

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

奥芬那君 柠檬酸盐, β-二甲基氨基乙基-2-甲基二苯甲醚 柠檬酸盐, 邻甲苯海明 柠檬酸盐

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C18H23NO · C6H8O7
化学文摘社编号:
4682-36-4
分子量:
461.50
NACRES:
NA.24
PubChem Substance ID:
329823606
UNSPSC Code:
41116107
EC Number:
225-137-5
MDL number:
MFCD00079197

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

奥芬那君, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

XLSFUJUURNFSCL-UHFFFAOYSA-N

InChI

1S/C18H23NO.C6H8O6/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16;7-4(8)1-3(6(11)12)2-5(9)10/h4-12,18H,13-14H2,1-3H3;3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

SMILES string

OC(=O)CC(CC(O)=O)C(O)=O.CN(C)CCOC(c1ccccc1)c2ccccc2C

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000101
traceable to USP 1479009

API family

orphenadrine

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

正在寻找类似产品? 访问 产品对比指南

相关类别

Biochem/physiol Actions

毒蕈碱型受体拮抗剂；H1 组胺受体拮抗剂；肌肉松弛剂。据报道，奥芬那君还可抑制去甲肾上素转运蛋白并且阻塞 NMDA 受体离子通道。

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Orphenadrine Citrate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography as well as spectrophotometry techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Orphenadrine Citrate is an analog of diphenhydramine antihistamine drug. It operates as a centrally acting skeletal muscle relaxant and effectively serves to relieve painful skeletal muscle spasms by working as an analgesics.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA8433 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Development of a capillary electrophoresis method for the determination of orphenadrine citrate in tablets in the presence of paracetamol.
Haj-Ali DN and Hamdan II
Saudi Pharmaceutical Journal : SPJ : The Official Publication of the Saudi Pharmaceutical Society, 18(4), 233-237 (2010)
Spectrophotometric determination of phenylephrine HCl and orphenadrine citrate in pure and in dosage forms.
Shama SA
Journal of Pharmaceutical and Biomedical Analysis, 30(4), 1385-1392 (2002)
Khaled Darwish et al.
Chemical & pharmaceutical bulletin, 60(11), 1426-1436 (2012-11-06)
New, simple, rapid and precise reversed-phase high-performance liquid chromatographic method was developed for the simultaneous determination of orphenadrine citrate, caffeine and aspirin in presence of aspirin degradation products, orphenadrine citrate and caffeine process related impurities, and excipients. Good resolution and

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持