PHR2438
4,7-二氯喹啉
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
4,7-Dichloroquinoline
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关于此项目
经验公式（希尔记法）:
C9H5Cl2N
化学文摘社编号:
分子量:
198.05
Beilstein:
125359
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24
生物来源
synthetic
质量水平
等级
certified reference material
pharmaceutical secondary standard
Agency
EP
USP
traceable to USP 1118328
蒸汽压
0.0000811 kPa ( 25 °C)
API类
chloroquine
表单
crystalline
包装
pkg of 50 mg
颜色
white to brown
pH值（酸碱度）
3.86 (24.9 °C)
沸点
298.4 °F (148°C)
mp
81-83 °C (lit.)
溶解性
water: slightly soluble 0.037 g/L at 25 °C
ethanol: freely soluble
ether: freely soluble
密度
1.31 g/cm3 at 20 °C (971.4 hPa)
应用
pharmaceutical
储存温度
2-30°C
SMILES字符串
Clc1ccc2c(Cl)ccnc2c1
InChI
1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H
InChI key
HXEWMTXDBOQQKO-UHFFFAOYSA-N
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一般描述
Chloroquine Related Compound A is an impurity of chloroquine, a 9-aminoquinoline drug that effectively inhibits viral infections in humans.
应用
Chloroquine Related Compound A can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.
Chloroquine Related Compound A can be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.
分析说明
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC4608 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
警示用语：
Warning
危险分类
Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Vincent MJ, et al.
Virology Journal, 2(1), 1-10 (2005)
Chloroquine Phosphate USP Monograph
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 959-959 (2020)
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