PHR2629
羟基脲
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
羟基尿素
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线性分子式:
NH2CONHOH
化学文摘社编号:
分子量:
76.05
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
1741548
MDL number:
产品名称
羟基脲, Pharmaceutical Secondary Standard; Certified Reference Material
SMILES string
NC(=O)NO
InChI
1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
InChI key
VSNHCAURESNICA-UHFFFAOYSA-N
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0000119
traceable to USP 1332000
API family
hydroxyurea
form
solid
CofA
current certificate can be downloaded
packaging
pkg of 300 mg
application(s)
pharmaceutical small molecule
storage temp.
2-8°C
Quality Level
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Biochem/physiol Actions
抗肿瘤剂。通过形成自由基硝基氧灭活核糖核苷还原酶，自由基硝基氧可结合到酶活性位点的酪氨酰自由基。这可阻断脱氧核苷酸的合成，从而抑制 DNA 合成，并且诱导细胞周期同步化或 S-期细胞死亡。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC5960 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Danger
hcodes
Hazard Classifications
Muta. 1B - Repr. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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