PHR3051
米托蒽醌 二盐酸盐
pharmaceutical secondary standard, certified reference material
别名:
1,4-二羟基-5,8-双-[[2-[（2-羟乙基）氨基] 乙基] 氨基]-9,10-蒽二酮 二盐酸盐
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关于此项目
经验公式（希尔记法）:
C22H28N4O6 · 2HCl
化学文摘社编号:
分子量:
517.40
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24
等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to USP 1445200
CofA
current certificate can be downloaded
包装
pkg of 50 mg
应用
pharmaceutical
SMILES字符串
Cl[H].Cl[H].OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12
InChI
1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H
InChI key
ZAHQPTJLOCWVPG-UHFFFAOYSA-N
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一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
生化/生理作用
米托蒽醌是一种细胞抑制性蒽二酮，可嵌入 DNA 中，通过稳定拓扑异构酶 II 与 DNA 的可裂解复合物，增加双链断裂的发生率。米托蒽醌还表现出广泛的免疫抑制活性，抑制各类淋巴细胞增殖并诱导抗原提呈 T 细胞凋亡。它在临床上用作抗白血病和实体瘤的化疗药物以及多发性硬化症的免疫系统调节剂。
分析说明
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
其他说明
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
警示用语：
Danger
危险声明
危险分类
Muta. 1B - Repr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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