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关于此项目
经验公式（希尔记法）:
C20H24N2O2 · 0.5H2O4S · H2O
化学文摘社编号:
分子量:
391.47
UNSPSC Code:
12352210
NACRES:
NA.21
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6113937
agency
USP/NF, meets USP testing specifications
mol wt
monograph mol wt. 782.94
mp
~225 °C (dec.) (lit.)
antibiotic activity spectrum
parasites
mode of action
enzyme | inhibits
SMILES string
O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
InChI
1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
InChI key
ZHNFLHYOFXQIOW-LPYZJUEESA-N
Application
Use to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites, the toxicity of heme (FP)-complexes and to inhibit mitochondrial ATP-regulated potassium channel.
Biochem/physiol Actions
钾通道阻滞剂。抗疟疾
钾通道阻滞剂。抗疟疾、抗胆碱能、抗高血压和降血糖剂；最初从南美树木的金鸡纳科中分离出来的生物碱。
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
此项目有
J P Mooney et al.
Mucosal immunology, 7(6), 1302-1311 (2014-03-29)
Coinfection can markedly alter the response to a pathogen, thereby changing its clinical presentation. For example, non-typhoidal Salmonella (NTS) serotypes are associated with gastroenteritis in immunocompetent individuals. In contrast, individuals with severe pediatric malaria can develop bacteremic infections with NTS
Eva Woltmann et al.
Analytical and bioanalytical chemistry, 406(25), 6347-6362 (2014-08-12)
High production output of solid pharmaceutical formulations requires fast methods to ensure their quality. Likewise, fast analytical procedures are required in forensic sciences, for example at customs, to substantiate an initial suspicion. We here present the design and the optimization
Jie Ma et al.
Talanta, 143, 205-211 (2015-06-17)
Hollow cross-linked fluorescent carbon nitride nanoparticles (CNNPs) were fabricated via a facile one-pot solvothermal process. The obtained CNNPs were characterized by multiple analytical techniques including transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), solid-state nuclear magnetic resonance
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| Q0132-25G | 04061838588784 |
| Q0132-10G | 04061838588777 |
| Q0132-50G | 04061838588791 |