R7635
罗硝唑
analytical standard
别名:
1-甲基-2-(氨基甲酰氧甲基)-5-硝基咪唑
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关于此项目
经验公式（希尔记法）:
C6H8N4O4
化学文摘社编号:
分子量:
200.15
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
231-675-1
MDL number:
InChI key
PQFRTXSWDXZRRS-UHFFFAOYSA-N
InChI
1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)
SMILES string
Cn1c(COC(N)=O)ncc1N(=O)=O
grade
analytical standard
assay
≥95%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
−20°C
Quality Level
General description
罗硝唑是一种硝基咪唑化合物，常用作抗原虫、抗菌剂。
Application
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
罗硝唑可作为参考标准品，通过配有紫外检测的高效液相色谱用于禽肉蛋中分析物的测定，并采用常压化学电离质谱法进行验证分析。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted nitroimidazoles.
Hoffer Max and Grunberg E
Journal of Medicinal Chemistry, 17(9), 1019-1020 (1974)
Elizabeth J Kather et al.
Journal of veterinary internal medicine, 21(5), 966-970 (2007-10-18)
The nitroimidazole, ronidazole, has been demonstrated to have in vitro and in vivo activity against the protozoan Tritrichomonas foetus in cats. The purpose of this study was to evaluate the in vitro susceptibility of feline T. foetus isolates obtained from
Determination of dimetridazole, ronidazole and their common metabolite in poultry muscle and eggs by high performance liquid chromatography with UV detection and confirmatory analysis by atmospheric pressure chemical ionisation mass spectrometry.
Sams JM, et al.
Analyst, 123(1-2), 2545-2549 (1998)
J L Gookin et al.
Journal of veterinary internal medicine, 24(4), 1003-1007 (2010-05-25)
The mainstays of treatment for clinically important trichomonad infections are the 5-nitroimidazoles. Metronidazole resistance of feline Tritrichomonas foetus is presumed because of common treatment failure, and tinidazole does not consistently eradicate infection. To date, ronidazole is the only drug demonstrated
Malcolm Holliday et al.
Journal of feline medicine and surgery, 11(2), 131-134 (2008-09-09)
Faecal samples from 74 cats with chronic large bowel diarrhoea that were living in a rescue colony in Italy, were submitted for assessment of Tritrichomonas foetus by direct microscopy of faecal smears (n=20) and T foetus-specific culture (n=74), with confirmation
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