R7774
核黄素5′-磷酸盐 钠盐 水合物
meets USP testing specifications
别名:
黄素单核苷酸
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关于此项目
经验公式（希尔记法）:
C17H20N4NaO9P · xH2O
分子量:
478.33 (anhydrous basis)
PubChem Substance ID:
eCl@ss:
34058005
UNSPSC Code:
12352205
NACRES:
NA.21
EC Number:
204-988-6
MDL number:
Quality Level
agency
USP/NF, meets USP testing specifications
assay
73.0-79.0% dry basis (BASED ON % RIBOFLAVIN)
form
powder
application(s)
pharmaceutical (small molecule)
storage temp.
−20°C
SMILES string
O.[Na+].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O)c2cc1C
InChI
1S/C17H21N4O9P.Na.H2O/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);;1H2/q;+1;/p-1/t11-,12+,14-;;/m0../s1
InChI key
BHRVCJBIICJWTH-APQIITSESA-M
General description
核黄素-5′-磷酸盐（黄素单核苷酸（FMN））是一种维生素B12衍生物，含有异恶嗪环系统。
Application
核黄素-5′-磷酸钠盐水合物已被用于：
- 作为光敏剂评估 体外 光动力疗法（PDT）对真菌的疗效
- 体内 评估其在大鼠角膜中的递送
- 作为维生素和生长因子储存混合物的组成部分
Biochem/physiol Actions
核黄素-5′-磷酸（黄素单核苷酸（FMN））在中间代谢中充当辅酶。通过黄素激酶磷酸化维生素B12可生成FMN。
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
Riboflavin's impact on cell culture systems for manufacturing proteins and monoclonal antibodies discussed.
Cell isolation and culture
WormBook: The Online Review of C. elegans Biology (2005)
Riboflavin (vitamin B2)
Handbook of vitamins, 255-273 (2013)
Rose bengal photodynamic antimicrobial therapy to inhibit Pseudomonas aeruginosa keratitis isolates.
Heather Durkee et al.
Lasers in medical science, 35(4), 861-866 (2019-12-25)
To evaluate the in vitro efficacy of rose bengal and riboflavin photodynamic antimicrobial therapy for inhibition the growth of four Pseudomonas aeruginosa (P. aeruginosa) isolates. Four different clinical P. aeruginosa isolates were collected from patients with confirmed keratitis. Each strain
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| R7774-10G | 04061836696870 |
| R7774-100G | 04061833623510 |
| R7774-25G | 04061838801999 |