SMB01344
N-Methyl-4-pyridone-5-carboxamide
别名:
1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide, 1,4-Dihydro-1-methyl-4-oxo-nicotinamide, 1-Methyl-1,4-dihydro-4-oxo-3-pyridinecarboxamide, 1-Methyl-4-pyridone-3-carboxamide, 1-Methyl-4-pyridone-5-carboxamide, 4-Py, 4PY, Me4PY, Met4PY, N1-Methyl-4-pyridone-3-carboxamide, N1-Methyl-4-pyridone-5-carboxamide
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选择尺寸
关于此项目
经验公式（希尔记法）:
C7H8N2O2
化学文摘社编号:
分子量:
152.15
UNSPSC Code:
12352205
NACRES:
NA.77
MDL number:
SMILES string
[n]1(cc([c](cc1)=O)C(=O)N)C
InChI
1S/C7H8N2O2/c1-9-3-2-6(10)5(4-9)7(8)11/h2-4H,1H3,(H2,8,11)
InChI key
KTLRWTOPTKGYQY-UHFFFAOYSA-N
assay
≥95% (HPLC)
form
solid
Quality Level
Application
Metabolomics research
General description
N1-methyl-4-pyridone-5-carboxamide is involved in nicotinate and nicotinamide metabolism.
Other Notes
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.
Yoshino, et al.
Science (New York, N.Y.), 372, 1224-1229 (2021)
Aurélie Lenglet et al.
Toxins, 8(11) (2016-11-18)
N-methyl-2-pyridone-5-carboxamide (2PY, a major metabolite of nicotinamide, NAM) was recently identified as a uremic toxin. Recent interventional trials using NAM to treat high levels of phosphorus in end-stage renal disease have highlighted new potential uremic toxicities of 2PY. In the
Renata Novak Kujundžić et al.
International journal of molecular sciences, 22(11) (2021-06-03)
The activity of nicotinamide N-methyltransferase (NNMT) is tightly linked to the maintenance of the nicotinamide adenine dinucleotide (NAD+) level. This enzyme catalyzes methylation of nicotinamide (NAM) into methyl nicotinamide (MNAM), which is either excreted or further metabolized to N1-methyl-2-pyridone-5-carboxamide (2-PY)
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