SMB01354
Losartan carboxylic acid
≥95% (HPLC)
别名:
EXP3174, 2-Butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid, E-3174, EXP 3174, EXP-3174
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C22H21ClN6O2
化学文摘社编号:
分子量:
436.89
UNSPSC Code:
12352106
NACRES:
NA.21
MDL number:
产品名称
Losartan carboxylic acid, ≥95% (HPLC)
SMILES string
Clc1nc([n](c1C(=O)O)Cc2ccc(cc2)c3c(cccc3)c4[nH]nnn4)CCCC
InChI
1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28)
InChI key
ZEUXAIYYDDCIRX-UHFFFAOYSA-N
assay
≥95% (HPLC)
form
solid
shipped in
wet ice
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
Metabolomics research
General description
Losartan Carboxylic Acid (E-3174) is an active carboxylic acid metabolite of Losartan. Losartan Carboxylic Acid is a potent and selective angiotensin II receptor type 1 (AT1) antagonist.
Other Notes
For additional information on our range of Biochemicals, please complete this form.
signalword
Danger
hcodes
Hazard Classifications
Lact. - Repr. 1B - Skin Sens. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Eleni Karatza et al.
Basic & clinical pharmacology & toxicology, 126(3), 193-202 (2019-09-13)
Losartan presents multiple peaks in the concentration-time profile. This characteristic can be attributed to gastric emptying, which is known to significantly affect the disposition of highly soluble and permeable compounds. The aim of this study was to develop a population
L L Chang et al.
Journal of medicinal chemistry, 36(17), 2558-2568 (1993-08-20)
A series of 2,4-dihydro-2,4,5-trisubstituted-3H-1,2,4-triazol-3-ones was prepared via several synthetic routes and evaluated as AII receptor antagonists in vitro and in vivo. The preferred compounds contained a [2'-(5-tetrazolyl)biphenyl-4-yl]methyl side chain at N4 and an n-butyl group at C5. A number of
A Gromotowicz-Poplawska et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 70(3) (2019-10-01)
The aim of the study was to evaluate the effect of an active metabolite of losartan - EXP3174 - on a performed venous thrombus in hypertensive rat. The contribution of coagulation and fibrinolytic systems as well as platelets in the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持