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Merck
CN

SYNPLE-B021

Reagent-cartridge Silyl deprotection

Synple

别名:

Synple 2

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UNSPSC Code:
12352401
NACRES:
NA.22
MDL number:
MFCD32903606

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SMILES string

[s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C

InChI key

HVPZHRHEHKZOOJ-TYBLODHISA-N

reaction suitability

reaction type: Alcohol Protection

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General description

Reagent-cartridge Silyl deprotection is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the silyl deprotection of primary and secondary alcohols. The cartridge contains all necessary reagents to perform the deprotection of TBS, TES, and TIPS protected alcohols.

Scale: up to 0.5 mmol

Compatible protecting groups: TBS, TES, TIPS (primary or secondary alcohols)

Cartridge contents:

  • pTsOH•H2O (for deprotection)
  • Silica supported triethylamine (for purification)
Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform
  • Time savings – pre-installed protocols have been highly optimized, which obviates the need for the user’s own reaction development and optimization
  • Easy to use – protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
  • Safety – all chemicals are contained in the system, minimizing the user’s exposure
  • Set-up reaction in less than 5 minutes
  • Small footprint
  • Plug & Play system – simple installation
  • Reaction temperatures from 25 °C – 80 °C
  • Cartridges available for many different reactions
  • Prefilled with all required reagents
  • RFID chip containing optimized reaction protocol

Other Notes

References
An integrated console for capsule-based, automated organic synthesis

Legal Information

Product of Synple Chem AG

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GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

8B - Non-combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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商品

Synple Automatic Synthesizer & Reagent Cartridges

Discover Synple 2, an automated organic chemical synthesis system that allows researchers to have their products generated for them while reducing both human error and manual labor.

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