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Merck
CN

V0500

L -缬氨酸

≥98% (HPLC), suitable for thin layer chromatography (TLC)

别名:

(S)-α-缬氨酸, L-2-氨基-3-二甲基丁酸

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关于此项目

线性分子式:
(CH3)2CHCH(NH2)CO2H
化学文摘社编号:
分子量:
117.15
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-773-6
MDL number:
Beilstein/REAXYS Number:
1721136
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产品名称

L -缬氨酸, reagent grade, ≥98% (HPLC)

InChI key

KZSNJWFQEVHDMF-BYPYZUCNSA-N

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1

SMILES string

CC(C)[C@H](N)C(O)=O

grade

reagent grade

assay

≥98% (HPLC)

form

powder

technique(s)

thin layer chromatography (TLC): suitable

color

white

mp

295-300 °C (subl.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

Quality Level

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Application

  • L-Valine一直用作薄层色谱的标准品。
  • 它是Grace′s antheraea培养基的补充剂,用于培养无脊椎动物的细胞和组织。
  • 也被用于制备饥饿培养基,以研究relA基因在大肠杆菌抗生素抗性中的作用。

Biochem/physiol Actions

缬氨酸是必需氨基酸,参与谷氨酰胺和丙氨酸的生物合成。缬氨酸是支链氨基酸(BCAA),维持着BCAA之间的平衡。L-缬氨酸是一种能量燃料。长期缺乏 L-缬氨酸会导致生长不足、器官损伤和肌肉质量损失。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Martin Kohlmeier
Nutrient Metabolism: Structures, Functions, and Genes, 390-390 (2015)
Preparation of several media for the culture of tissues and cells from invertebrates.
Vaughn
TCA Manual, 527-537 (1977)
On the limited role of relA in kanamycin and amino acid starvation induced stringency and subsequent antibiotic cross-protection in Escherichia coli
Chiang
Journal of Experimental Microbiology and Immunology, 15, 59-63 (2011)
Zhesi Zhu et al.
Nucleic acids research, 49(1), 177-189 (2020-12-15)
Short-chain acylations of lysine residues in eukaryotic proteins are recognized as essential posttranslational chemical modifications (PTMs) that regulate cellular processes from transcription, cell cycle, metabolism, to signal transduction. Lysine butyrylation was initially discovered as a normal straight chain butyrylation (Knbu).
Zhe Yang et al.
Cell research, 28(10), 1013-1025 (2018-09-14)
Adequate protein intake is crucial for the survival and well-being of animals. How animals assess prospective protein sources and ensure dietary amino acid intake plays a critical role in protein homeostasis. By using a quantitative feeding assay, we show that

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