Y0000016
普鲁泊福
European Pharmacopoeia (EP) Reference Standard
别名:
普鲁泊福, 2,6-双(1-甲基乙基)苯酚
等级
pharmaceutical primary standard
蒸汽压
5.6 mmHg ( 100 °C)
API类
propofol
制造商/商品名称
EDQM
折射率
n20/D 1.514 (lit.)
沸点
256 °C/764 mmHg (lit.)
mp
18 °C (lit.)
密度
0.962 g/mL at 25 °C (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
CC(C)c1cccc(C(C)C)c1O
InChI
1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
InChI key
OLBCVFGFOZPWHH-UHFFFAOYSA-N
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警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
Philippe E Dubois et al.
European journal of anaesthesiology, 31(8), 404-410 (2013-07-26)
Disturbances in the thumb's movement interfere with the functioning of acceleromyography in many clinical settings. The short and light (SL) train-of-four (TOF)-Tube is a new version of a rigid tubular device that was designed to protect the thumb from external
Kim van Loon et al.
Anesthesia and analgesia, 119(1), 49-55 (2014-05-20)
Propofol, a short-acting hypnotic drug, is increasingly administered by a diverse group of specialists (e.g., cardiologists, gastroenterologists) during diagnostic and therapeutic procedures. Standard monitoring during sedation comprises continuous pulse oximetry with visual assessment of the patient's breathing pattern. Because undetected
Muhammad Suleman Khan et al.
Basic & clinical pharmacology & toxicology, 115(6), 565-570 (2014-06-04)
A variety of techniques have been developed to monitor the depth of anaesthesia. Propofol's pharmacokinetics and response vary greatly, which might be explained by genetic polymorphisms. We investigated the impact of genetic variations on dosage, anaesthetic depth and recovery after
A J Thomson et al.
Anaesthesia, 69(5), 420-428 (2014-04-18)
Debate continues over the most appropriate blood-brain equilibration rate constant (ke0) for use with the Marsh pharmacokinetic model for propofol. We aimed to define the optimal ke0 value. Sixty-four patients were sedated with incremental increases in effect-site target concentration of
Cynthia Ménard et al.
Radiology, 274(1), 181-191 (2014-09-10)
To determine if the integration of diagnostic magnetic resonance (MR) imaging and MR-guided biopsy would improve target delineation for focal salvage therapy in men with prostate cancer. Between September 2008 and March 2011, 30 men with biochemical failure after radiation
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