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经验公式（希尔记法）:
C12H17NO2
化学文摘社编号:
分子量:
207.27
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
产品名称
环吡酮胺, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3
SMILES string
ON1C(C2CCCCC2)=CC(C)=CC1=O
InChI key
SCKYRAXSEDYPSA-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
ciclopirox
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Ciclopirox EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
M Bohn et al.
Journal of the American Academy of Dermatology, 43(4 Suppl), S57-S69 (2000-10-29)
Ciclopirox is a synthetic hydroxypyridone antifungal agent. In contrast to the azoles, glucuronidation is the main metabolic pathway of ciclopirox; therefore interactions with drugs metabolized via the cytochrome P450 system are unlikely Ciclopirox is also distinct from the common systemic
Aditya K Gupta et al.
International journal of dermatology, 42 Suppl 1, 3-9 (2003-08-05)
Ciclopirox is a broad-spectrum antifungal agent that also exhibits anti-inflammatory and antibacterial activity. The lotion and cream formulations of ciclopirox are effective in many types of infection, including tinea corporis/cruris, tinea pedis, cutaneous candidiasis, pityriasis (tinea) versicolor, and seborrheic dermatitis.
A K Gupta et al.
Journal of the American Academy of Dermatology, 43(4 Suppl), S96-102 (2000-10-29)
Ciclopirox nail lacquer solution 8% has been shown to be effective in the treatment of dermatophyte onychomycosis of mild to moderate severity Other studies report the effectiveness of ciclopirox nail lacquer in onychomycosis caused by Candida sp and nondermatophyte molds.
Aditya K Gupta et al.
International journal of dermatology, 45(1), 66-69 (2006-01-24)
Seborrheic dermatitis is a chronic superficial fungal infection of the skin, particularly affecting sites rich in sebaceous glands. Although the precise etiology of seborrheic dermatitis is uncertain, yeasts of the genus Malassezia are known to play a causative role. Ciclopirox
Ciclopirox: an overview.
A K Gupta
International journal of dermatology, 40(5), 305-310 (2001-09-14)
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