生物来源
synthetic
等级
pharmaceutical primary standard
Agency
EP
API类
dihydrotachysterol
表单
solid
制造商/商品名称
EDQM
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
−20°C
SMILES字符串
C[C@@H]([C@@]1([H])CC[C@@]2([H])/C(CCC[C@@]21C)=C/C=C3[C@@H](C)CC[C@H](O)C/3)/C=C/[C@H](C)C(C)C
InChI
1S/C28H46O/c1-19(2)20(3)12-13-22(5)25-16-17-26-23(10-8-18-28(25,26)6)14-15-24-21(4)9-7-11-27(24)29/h12-15,19-22,25-27,29H,7-11,16-18H2,1-6H3/b13-12+,23-14+,24-15+/t20-,21-,22+,25?,26?,27-,28+/m0/s1
InChI key
DTSXXSAWQHPLEF-GFVAUXBKSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Dihydrotachysterol (DHT) is a biologically active synthetic analog of vitamin D. It aids in promoting active calcium and phosphate intestinal absorption. It is also beneficial in the treatment of hypoparathyroidism.
应用
Dihydrotachysterol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Aquatic Chronic 4
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
A L Voigts et al.
Archives of internal medicine, 143(5), 960-963 (1983-05-01)
The available data with regard to the use of calciferol, dihydrotachysterol, and calcifediol in the management of renal insufficiency are reviewed. Very limited data are available with regard to calciferol therapy; with the advent of more active metabolites, the use
I Quack et al.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 113(7), 376-380 (2005-07-19)
The half synthetic Vitamin D analogue dihydrotachysterol (DHT) is widely used for hypocalcaemic hypoparathyroidism following surgical removal of parathyroids. Such treatment generally initiated by surgeons right after surgery has to be continued in clinical practice. Unfortunately, the required careful monitoring
In vivo metabolism of the vitamin D analog, dihydrotachysterol. Evidence for formation of 1 alpha, 25-and 1 beta, 25-dihydroxy-dihydrotachysterol metabolites and studies of their biological activity.
Qaw F, et al.
Test, 268(1), 282-292 (1993)
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