Y0000636
Modafinil for system suitability
European Pharmacopoeia (EP) Reference Standard
别名:
Modafinil, 2-[(Diphenylmethyl)sulfinyl]acetamide
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关于此项目
经验公式（希尔记法）:
C15H15NO2S
化学文摘社编号:
分子量:
273.35
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
pharmaceutical primary standard
API类
modafinil
制造商/商品名称
EDQM
drug control
Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
NC(=O)CS(=O)C(c1ccccc1)c2ccccc2
InChI
1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)
InChI key
YFGHCGITMMYXAQ-UHFFFAOYSA-N
基因信息
human ... SLC6A3(6531)
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Modafinil for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
生化/生理作用
Modafinil is a central nervous system vigilance promoting agent, which posseses neuroprotective properties.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Repr. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
此项目有
Mariana Raineri et al.
PloS one, 7(10), e46599-e46599 (2012-10-12)
Methamphetamine is a drug of abuse that can cause neurotoxic damage in humans and animals. Modafinil, a wake-promoting compound approved for the treatment of sleeping disorders, is being prescribed off label for the treatment of methamphetamine dependence. The aim of
Derek Dunn et al.
Chemical biology & drug design, 81(3), 433-435 (2012-12-05)
Utilizing atypical wake-promoting agent modafinil (inactive in both rH(3) and hH(3) binding assays) as a launching pad, a series of sulfinyl- and sulfone-derived H(3) receptor inverse agonists were developed. Brain-permeable compound 27, a potent member of the series displayed excellent
Trends in on-label and off-label modafinil use in a nationally representative sample.
Renée A Peñaloza et al.
JAMA internal medicine, 173(8), 704-706 (2013-04-05)
Arterial hypertension and resistance to antihypertensive treatment: a new adverse drug reaction with modafinil.
Jacques Amar et al.
Therapie, 68(1), 53-54 (2013-03-15)
Brigitte Lesur et al.
Chemical biology & drug design, 81(3), 429-432 (2012-11-01)
In search of a next generation molecule to the novel wake-promoting agent modafinil, a series of aryl-heteroayl-derived wakefulness enhancing agents (in rats) was developed. From this work, compound 16 was separated into its enantiomers to profile them individually.
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