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01148

氟化钠

Name: 氟化钠
Brand: SIGALD

puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

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关于此项目

线性分子式:

NaF

化学文摘社编号:

7681-49-4

分子量:

41.99

UNSPSC Code:

12352302

eCl@ss:

38050104

PubChem Substance ID:

329747226

EC Number:

231-667-8

NACRES:

NA.21

MDL number:

MFCD00003524

Assay:

98.5-100.5% (calc. to the dried substance)

Form:

powder

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属性

vapor pressure

1.4 mmHg ( 0 °C)

Quality Level

200

grade

puriss.

assay

98.5-100.5% (calc. to the dried substance)

form

powder

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

acidity or alkalinity, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.002% heavy metals (as Pb), ≤0.1% free alkali (as NaOH), ≤0.2% free acid (as HF), ≤0.2% sodium hexafluorosilicate (Na₂SiF₆)

loss

≤0.5% loss on drying, 150 °C

mp

993 °C (lit.)

anion traces

chloride (Cl^-): ≤100 mg/kg, sulfate (SO₄^2-): ≤200 mg/kg

cation traces

Fe: ≤50 mg/kg

suitability

complies for appearance of solution

SMILES string

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

说明

General description

氟化钠 (NaF) 是一种金属卤化物。有作为龋齿预防剂的报道。是应用最广泛的用于保存血液中葡萄糖的防腐剂。据报道，它能稳定肝微粒体葡萄糖-6-P 磷酸水解酶。

Application

氟化钠可用作氟化剂，用于通过复分解反应合成芳香族和脂肪族氟化物。可用于制备裂解缓冲液。

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pictograms

GHS06

signalword

Danger

hcodes

H301,H315,H319

pcodes

P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

supp_hazards

EUH032

flash_point_f

Not applicable

flash_point_c

Not applicable

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

危险化学品

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The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl.

J G Drachman et al.

The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)

c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells

Effectiveness of sodium fluoride as a preservative of glucose in blood.

Chan AY, et al.

Clinical Chemistry, 35(2), 315-317 (1989)

Aluminum ions are required for stabilization and inhibition of hepatic microsomal glucose-6-phosphatase by sodium fluoride.

A J Lange et al.

The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)

Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of

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