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Merck
CN

01148

氟化钠

puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

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关于此项目

线性分子式:
NaF
化学文摘社编号:
7681-49-4
分子量:
41.99
UNSPSC Code:
12352302
eCl@ss:
38050104
PubChem Substance ID:
329747226
EC Number:
231-667-8
NACRES:
NA.21
MDL number:
MFCD00003524
Assay:
98.5-100.5% (calc. to the dried substance)
Form:
powder

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InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

vapor pressure

1.4 mmHg ( 0 °C)

grade

puriss.

assay

98.5-100.5% (calc. to the dried substance)

form

powder

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

acidity or alkalinity, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.002% heavy metals (as Pb), ≤0.1% free alkali (as NaOH), ≤0.2% free acid (as HF), ≤0.2% sodium hexafluorosilicate (Na2SiF6)

loss

≤0.5% loss on drying, 150 °C

mp

993 °C (lit.)

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤200 mg/kg

cation traces

Fe: ≤50 mg/kg

suitability

complies for appearance of solution

Quality Level

200

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General description

氟化钠 (NaF) 是一种金属卤化物。有作为龋齿预防剂的报道。是应用最广泛的用于保存血液中葡萄糖的防腐剂。据报道，它能稳定肝微粒体葡萄糖-6-P 磷酸水解酶。

Application

氟化钠可用作氟化剂，用于通过复分解反应合成芳香族和脂肪族氟化物。可用于制备裂解缓冲液。

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

supp_hazards

EUH032

flash_point_f

Not applicable

flash_point_c

Not applicable

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
STBL0919
STBK6711
STBK4579
STBK4450
STBK3254

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J G Drachman et al.
The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)
c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells
Effectiveness of sodium fluoride as a preservative of glucose in blood.
Chan AY, et al.
Clinical Chemistry, 35(2), 315-317 (1989)
A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
Synthesis of fluorides by metathesis with sodium fluoride.
Tullock CW and Coffman DD.
The Journal of Organic Chemistry, 25(11), 2016-2019 (1960)
Hye-Jin Lee et al.
The Kaohsiung journal of medical sciences, 31(6), 303-308 (2015-06-05)
Dental caries preventive agents, such as sodium fluoride (NaF) and bamboo salt (BS), are known to cause cellular growth that is characterized by morphological and gene expression changes. This study was designed to investigate the dual effect of NaF and
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