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Merck
CN

04273

磷酸钠 二元 十二水合物

meets analytical specification of Ph. Eur., BP, E339, 98.5-102.5% (T)

别名:

磷酸氢二钠, 磷酸氢二钠 十二水合物

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关于此项目

线性分子式:
Na2HPO4 · 12H2O
化学文摘社编号:
分子量:
358.14
PubChem Substance ID:
UNSPSC Code:
12161700
NACRES:
NA.25
EC Number:
231-448-7
MDL number:
Assay:
98.5-102.5% (T)
Form:
crystals
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Quality Level

agency

meets analytical specifications of BP, meets analytical specifications of Ph. Eur.

assay

98.5-102.5% (T)

form

crystals

quality

meets analytical specification of Ph. Eur., BP, E339

impurities

reducing matter, complies, residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤1.0% NaH2PO4, 57-61% water (Karl Fischer)

loss

57-61% loss on drying

pH

8.4-9.6 (20 °C, 1%)

anion traces

chloride (Cl-): ≤10 mg/kg, fluoride (F-): ≤10 mg/kg, sulfate (SO42-): ≤100 mg/kg

cation traces

As: ≤1 mg/kg, Cd: ≤1 mg/kg, Cu: ≤20 mg/kg, Fe: ≤10 mg/kg, Hg: ≤1 mg/kg, K: ≤50 mg/kg, Pb: ≤4 mg/kg, Zn: ≤10 mg/kg

suitability

complies for appearance of solution

SMILES string

O.O.O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

1S/2Na.H3O4P.12H2O/c;;1-5(2,3)4;;;;;;;;;;;;/h;;(H3,1,2,3,4);12*1H2/q2*+1;;;;;;;;;;;;;/p-2

InChI key

DGLRDKLJZLEJCY-UHFFFAOYSA-L

Application


  • 碱化组分对挤出/球化法制备的基质颗粒的影响研究: 本文研究了十二水磷酸氢二钠作为基质颗粒碱化剂的作用,展示了其在改善颗粒理化性质方面的应用,这对于药物控释系统至关重要(Hamedelniel EI, Bajdik J, Kasa P Jr, Pintye-Hodi K, 2012)。



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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

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Elevated serum phosphate has emerged as a major risk factor for vascular calcification. The sodium-dependent phosphate cotransporter, PiT-1, was previously shown to be required for phosphate-induced osteogenic differentiation and calcification of cultured human vascular smooth muscle cells (VSMCs), but its



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