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Merck
CN

34943

二甲基亚砜

puriss. p.a., dried, ≤0.02% water

别名:

DMSO, 甲基亚砜

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关于此项目

线性分子式:
(CH3)2SO
化学文摘社编号:
分子量:
78.13
UNSPSC Code:
12191502
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-664-3
Beilstein/REAXYS Number:
506008
MDL number:
Assay:
≥99.9% (GC)
Vapor pressure:
0.42 mmHg ( 20 °C)
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InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

SMILES string

CS(C)=O

Quality Level

vapor pressure

0.42 mmHg ( 20 °C)

grade

puriss. p.a.

assay

≥99.9% (GC)

form

liquid

autoignition temp.

573 °F

quality

dried

expl. lim.

42 %, 63 °F

impurities

≤0.0001% heavy metals (as Pb), ≤0.001% free acid (as H2SO4), ≤0.002% non-volatile matter, ≤0.02% water, ≤0.03% water (Karl Fischer)

density

1.10 g/mL (lit.)

cation traces

Fe: ≤1 mg/kg

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General description

二甲基亚砜(DMSO)是极性溶剂。由各种亲电子试剂(草酰氯)活化的 DMSO 已用于氧化各种醇(伯、仲、烯丙基、苄基、受阻和双环)。形成羰基化合物作为反应产物。由于其高稳定性,已提出将其用作甲基溶纤剂的替代溶剂用于茚三酮反应。

Application

二甲基亚砜(DMSO)已用作对 Mtb(结核分枝杆菌)H37Rv 宿主细胞进行的高通量化合物筛选研究中的溶剂。

Other Notes

有关二甲基亚砜混溶性的信息,请访问以下链接:
二甲基亚砜混溶性/不混溶性表

Disclaimer

在室温下容易过冷并缓慢重融。 固化产品可以通过加热至室温来重新液化,而不会损害产品。

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup


历史批次信息供参考:

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Christophe J Queval et al.
Journal of visualized experiments : JoVE, (83)(83), e51114-e51114 (2014-01-30)
Despite the availability of therapy and vaccine, tuberculosis (TB) remains one of the most deadly and widespread bacterial infections in the world. Since several decades, the sudden burst of multi- and extensively-drug resistant strains is a serious threat for the
Oxidation of alcohols by ?activated? dimethyl sulfoxide. A preparative, steric and mechanistic study.
Omura K and Swern D.
Tetrahedron, 34(11), 1651-1660 (1978)
Amino acid analysis: aqueous dimethyl sulfoxide as solvent for the ninhydrin reaction.
S Moore
The Journal of biological chemistry, 243(23), 6281-6283 (1968-12-10)
A RAPID PERMETHYLATION OF GLYCOLIPID, AND POLYSACCHARIDE CATALYZED BY METHYLSULFINYL CARBANION IN DIMETHYL SULFOXIDE.
S HAKOMORI
Journal of biochemistry, 55, 205-208 (1964-02-01)
Phillip McDonagh et al.
Veterinary microbiology, 174(3-4), 438-447 (2014-12-04)
Feline infectious peritonitis (FIP), a feline coronavirus (FCoV) induced disease, is almost invariably fatal with median life expectancy measured in days. Current treatment options are, at best, palliative. The objectives of this study were to evaluate a panel of nineteen

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