乙腈（MeCN，ACN）是一种脂肪族腈，通常用作反应溶剂以及有机合成中的化学中间体。由于MeCN低粘度、高洗脱强度和在水中的混溶性，在许多色谱技术中它被用作流动相溶剂。

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乙腈可作为溶剂，用于：      

• 固相多肽合成。     
• 唾液酸化反应。      
• 用NaBH₄还原硝酸铜盐合成铜纳米颗粒。在制备过程中，乙腈作为保护溶剂，防止纳米颗粒的氧化。      
• 通过Cu催化芳基碘和二苯基二硒醚的偶联反应制备二芳基硒醚。在此过程中，ACN也作为铜催化剂的配体，以增加其催化活性。

ACS溶剂品质满足或超过美国化学学会(ACS)的高标准，每种化合物都具有特定的检验规格。根据美国化学学会标准，ACS试剂级代表物质纯度足够用于大多数化学分析或反应。