Merck
CN

360589

Sigma-Aldrich

四氢呋喃

contains 250 ppm BHT as inhibitor, ACS reagent, ≥99.0%

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别名:
THF, 丁烯氧化物, 四亚甲基氧化物, 氧杂环戊烷
经验公式(希尔记法):
C4H8O
CAS号:
分子量:
72.11
Beilstein:
102391
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.21

等级

ACS reagent

质量水平

蒸汽密度

2.5 (vs air)

蒸汽压

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

检测方案

≥99.0%

形式

liquid

自燃温度

610 °F

包含

250 ppm BHT as inhibitor

expl. lim.

1.8-11.8 %

technique(s)

HPLC: suitable

杂质

≤0.015% peroxide (as H2O2)
≤0.05% water

蒸发残留物

≤0.03%

颜色

APHA: ≤20

折射率

n20/D 1.407 (lit.)

pH值(酸碱度)

~7

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

溶解性

water: soluble

密度

0.889 g/mL at 25 °C (lit.)

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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一般描述

四氢呋喃(THF)是一种杂环化合物(环醚)。无色、低粘度,在多种溶剂中具有优越的溶解性。广泛用作有机合成溶剂,常用于含有机金属化合物和Grignard试剂的反应。由于长期存放容易产生过氧化物,THF常添加丁羟甲苯(BHT)稳定剂。BHT能去除形成过氧化物所需的自由基。

应用

四氢呋喃(THF)可作为溶剂用于以下过程:

  • 有机合成
a) Grignard
b) 有机金属化合物
c) Reformatsky
D) 锂化
e) 氢化物还原
f) 金属催化偶联(Heck, Stile, Suzuki)
g) 路易斯介导反应
  • 结晶
  • 聚合如对乙酰氧基苯乙烯的RAFT(可逆加成断裂链转移)聚合。
  • 涂料
  • 作为O-供体配体,形成配位络合物
  • 作为高效液相色谱的流动相溶剂

特点和优势

ACS溶剂品质满足或超过美国化学学会(ACS)的高标准,每种化合物都具有特定的检验规格。根据美国化学学会标准,ACS试剂级代表物质纯度足够用于大多数化学分析或反应。

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2

补充剂危害

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

-6.2 °F - closed cup

闪点(°C)

-21.2 °C - closed cup

法规信息

危险化学品

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