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Merck
CN

01897

Sigma-Aldrich

腺苷-5'-二磷酸 二钠盐

≥90%

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别名:
ADP二钠盐, 腺苷 5′-ADP, 腺苷 5′-二磷酸二钠盐, 5′-ADP-Na2
经验公式(希尔记法):
C10H13N5Na2O10P2
CAS号:
分子量:
471.16
Beilstein:
7563620
EC 号:
MDL编号:
UNSPSC代码:
41106305
eCl@ss:
32160414
PubChem化学物质编号:
NACRES:
NA.51

质量水平

检测方案

≥90%

形式

powder or crystals

旋光性

[α]20/D −29.6±1°, c = 0.5% in 0.5 M Na2HPO4

杂质

≤10% water

储存温度

−20°C

SMILES字符串

[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H15N5O10P2.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChI key

ORKSTPSQHZNDSC-IDIVVRGQSA-L

应用

5′-二磷酸腺苷二钠盐用于在血液样本中的嘌呤能 G 蛋白耦联受体 P2Y12 激动剂血小板活化检测。

生化/生理作用

5′-二磷酸腺苷(ADP)是一种通过 ATP 合酶转化为 ATP 而参与能量储存和核酸代谢的腺嘌呤核苷酸。ADP 通过嘌呤受体 P2Y1 与 P2Y12 的相互作用影响血小板活化。 在通过ecto-ADP酶转化为腺苷后,通过腺苷受体抑制血小板活化。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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