噻康唑

Name: 噻康唑
Brand: SIGMA

97%

别名:

1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Thioconazole

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₁₆H₁₃Cl₃N₂OS

CAS Number:

65899-73-2

分子量:

387.71

EC 号:

265-973-8

MDL编号:

MFCD00057276

UNSPSC代码:

51302325

PubChem化学物质编号:

329747834

NACRES:

NA.85

方案

≥96.5% (HPLC)
96.5-103.5% (NT)
97%

表单

powder

颜色

white to off-white

抗生素抗菌谱

fungi
yeast

作用机制

cell membrane | interferes

SMILES字符串

Clc1ccc(C(Cn2ccnc2)OCc3ccsc3Cl)c(Cl)c1
Clc1ccc(C(Cn2ccnc2)OCc3ccsc3Cl)c(Cl)c1

InChI

1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2

InChI key

QXHHHPZILQDDPS-UHFFFAOYSA-N

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一般描述

Chemical structure: pyrimidine

应用

Tioconazole was used to study the synergistic mechanisms of antifungals on Candida albicans as well as significant drug-drug interactions in vivo.

生化/生理作用

Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast.It is more active than fluconazole or voriconazole against Candida glabrata mutant strains. It acts by membrane disruption and loss of intracellular ATP.