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03907

噻康唑

Name: 噻康唑
Brand: SIGMA

97%

别名:

1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Thioconazole

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关于此项目

经验公式（希尔记法）:

C₁₆H₁₃Cl₃N₂OS

化学文摘社编号:

65899-73-2

分子量:

387.71

PubChem Substance ID:

329747834

UNSPSC Code:

51302325

NACRES:

NA.85

EC Number:

265-973-8

MDL number:

MFCD00057276

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属性

Quality Segment

100

assay

≥96.5% (HPLC), 96.5-103.5% (NT), 97%

form

powder

color

white to off-white

antibiotic activity spectrum

fungi, yeast

mode of action

cell membrane | interferes

SMILES string

Clc1ccc(C(Cn2ccnc2)OCc3ccsc3Cl)c(Cl)c1

InChI

1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2

InChI key

QXHHHPZILQDDPS-UHFFFAOYSA-N

说明

General description

Chemical structure: pyrimidine

Application

Tioconazole was used to study the synergistic mechanisms of antifungals on Candida albicans as well as significant drug-drug interactions in vivo.

Biochem/physiol Actions

Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast.It is more active than fluconazole or voriconazole against Candida glabrata mutant strains. It acts by membrane disruption and loss of intracellular ATP.