04476
大麦芽碱
≥97.0% (HPLC)
别名:
2-(4-羟基苯基)-N,N-二甲基乙胺, 4-(2-二甲基氨基乙基)苯酚, N,N-二甲基酪胺, 对羟基-N,N-二甲基苯乙胺, 仙影拳碱, 大麦碱, 大麦胺, 大麦芽碱
质量水平
方案
≥97.0% (HPLC)
表单
powder or crystals
应用
metabolomics
vitamins, nutraceuticals, and natural products
SMILES字符串
CN(C)CCc1ccc(O)cc1
CN(C)CCc1ccc(O)cc1
InChI
1S/C10H15NO/c1-11(2)8-7-9-3-5-10(12)6-4-9/h3-6,12H,7-8H2,1-2H3
InChI key
KUBCEEMXQZUPDQ-UHFFFAOYSA-N
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应用
大麦芽碱适合用于研究芦苇金丝雀草生物碱对体外消化率的影响。它也适合作为标准品用于通过HPLC/二极管阵列检测分析对未发芽和发芽的大麦中内源大麦芽碱进行鉴定。大麦芽碱可作为分析参考材料，并用于研究苯乙胺型生物碱的活性。
生化/生理作用
大麦芽碱是一种生物碱，发现于植物，如麦芽和海藻的根中。它是酪氨酸代谢的一种代谢产物，可由酪胺通过先后两次的N-甲基化反应而进行生物合成，它可通过单胺氧化酶而被代谢。大麦芽碱是一种拟交感神经药，因偶尔能够在赛跑后的尿液样品中发现而引发对其药理作用的关注。大麦芽碱可通过抑制环磷腺苷酸（cAMP）的产生而对黑色素生成进行抑制。cAMP可参与到黑色素生成相关蛋白的表达。大麦芽碱可被用于抑制色素沉着。它从种子萌芽的第一天起就存在于大麦的根中，但其并不存在于种子中。
包装
无底玻璃瓶。内含物在插入的融合锥体内。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
涉药品监管产品
此项目有
The biogenesis of alkaloids. XVI. Hordenine metabolism in barley.
Frank, A. W. and Marion, L.
Canadian Journal of Chemistry, 34, 1641-1646 (1956)
[Not Available].
R HAZARD et al.
Comptes rendus des seances de la Societe de biologie et de ses filiales, 139, 630-630 (1945-07-01)
T Wainwright et al.
IARC scientific publications, (41)(41), 71-80 (1982-01-01)
NDMA is formed in malt because NOx reacts with certain amines in germinated barley when it is kilned. Hordenine is the major precursor of NDMA, although gramine and sarcosine can possibly contribute minor amounts. The hordenine is formed in the
Marwan Shabana et al.
Natural product research, 20(8), 710-714 (2006-06-07)
Four alkaloids of the phenethylamine derivatives have been isolated from the n-butanol fraction of the aerial parts of Stapelia hirsuta L. The structures of the isolated alkaloids were determined as N-acetyl hordenine (a new natural compound), hordenine, candicine and hordenine-1-O-beta-D-glucoside
Daopeng Tan et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 35(19), 2572-2575 (2010-12-24)
To investigate the alkaloids from Senecio scandens. Compounds were isolated with silica gel and Sephadex LH-20 column chromatography and their structures were determined by spectral analysis and chemical evidence. The hepatic cytotoxicity of isolated compounds was tested by MTT method
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