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关于此项目
经验公式(希尔记法):
C10H15NO
化学文摘社编号:
分子量:
165.23
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
208-710-4
MDL number:
Beilstein/REAXYS Number:
2207615
产品名称
大麦芽碱, ≥97.0% (HPLC)
SMILES string
CN(C)CCc1ccc(O)cc1
CN(C)CCc1ccc(O)cc1
InChI key
KUBCEEMXQZUPDQ-UHFFFAOYSA-N
InChI
1S/C10H15NO/c1-11(2)8-7-9-3-5-10(12)6-4-9/h3-6,12H,7-8H2,1-2H3
assay
≥97.0% (HPLC)
form
powder or crystals
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
Quality Level
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Application
大麦芽碱适合用于研究芦苇金丝雀草生物碱对体外消化率的影响。它也适合作为标准品用于通过HPLC/二极管阵列检测分析对未发芽和发芽的大麦中内源大麦芽碱进行鉴定。大麦芽碱可作为分析参考材料,并用于研究苯乙胺型生物碱的活性。
Biochem/physiol Actions
大麦芽碱是一种生物碱,发现于植物,如麦芽和海藻的根中。它是酪氨酸代谢的一种代谢产物,可由酪胺通过先后两次的N-甲基化反应而进行生物合成,它可通过单胺氧化酶而被代谢。大麦芽碱是一种拟交感神经药,因偶尔能够在赛跑后的尿液样品中发现而引发对其药理作用的关注。大麦芽碱可通过抑制环磷腺苷酸(cAMP)的产生而对黑色素生成进行抑制。cAMP可参与到黑色素生成相关蛋白的表达。大麦芽碱可被用于抑制色素沉着。它从种子萌芽的第一天起就存在于大麦的根中,但其并不存在于种子中。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Studies on the mechanism of action of monoamine oxidase: metabolism of N,N-dimethyltryptamine and N,N-dimethyltryptamine-N-oxide.
T E SMITH et al.
Biochemistry, 1, 137-143 (1962-01-01)
Hordenine content of the marine alga Mastocarpus stellatus and the algal food product carrageen.
Barwell, C.J., et al.
Phytotherapy Research, 3, 67-69 (1989)
A K Singh et al.
Forensic science international, 54(1), 9-22 (1992-04-01)
Hordenine cross-reacted with various enzyme linked immunosorbent assay (ELISA) or radioimmunoassay (RIA) kits used for the screening of urine samples. Morphine-ELISA kit was most sensitive, whereas etorphine- and buprenorphine-ELISA kits were least sensitive to hordenine cross-reactivity. Hordenine also interfered with
H J Hapke et al.
DTW. Deutsche tierarztliche Wochenschrift, 102(6), 228-232 (1995-06-01)
Hordenine is an ingredient of some plants which are used as feed for animals, i.e. in sprouting barley. After ingestion of such feed hordenine may be detected in blood or urine of horses which in case of racing horses may
C A Bourke et al.
Australian veterinary journal, 65(7), 218-220 (1988-07-01)
The acute toxicity for sheep of 3 alkaloids that occur in Phalaris acquatica was examined by intravenous and oral administration. The lowest tested dose rates that produced clinically observed signs were, for 5-methoxy dimethyltryptamine, 0.1 mg/kg body weight intravenously and
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