06880
4-氨基联苯胺 二盐酸盐
BioReagent, suitable for fluorescence, ≥99.0% (TLC)
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关于此项目
线性分子式:
H2NC6H4C(=NH)NH2·2HCl
化学文摘社编号:
分子量:
208.09
Beilstein:
3692927
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.32
产品线
BioReagent
方案
≥99.0% (TLC)
表单
powder or crystals
mp
>300 °C (lit.)
荧光
λex >300 nm in H2O
适用性
suitable for fluorescence
储存温度
2-8°C
SMILES字符串
Cl[H].Cl[H].NC(=N)c1ccc(N)cc1
Cl[H].Cl[H].NC(=N)c1ccc(N)cc1
InChI
1S/C7H9N3.2ClH/c8-6-3-1-5(2-4-6)7(9)10;;/h1-4H,8H2,(H3,9,10);2*1H
InChI key
GHEHNICLPWTXJC-UHFFFAOYSA-N
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分析说明
Emmax: none
其他说明
Competitive inhibitor of serine proteases; As a fluorescent probe for the active site of serine proteases
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
STUDIES ON THE ACTIVE CENTER OF TRYPSIN. THE BINDING OF AMIDINES AND GUANIDINES AS MODELS OF THE SUBSTRATE SIDE CHAIN.
M MARES-GUIA et al.
The Journal of biological chemistry, 240, 1579-1585 (1965-04-01)
Comparative studies on the inhibition of trypsin, plasmin, and thrombin by derivatives of benzylamine and benzamidine.
F Markwardt et al.
European journal of biochemistry, 6(4), 502-506 (1968-12-05)
S A Evans et al.
The Journal of biological chemistry, 257(6), 3014-3017 (1982-03-25)
p-Aminobenzamidine is weakly fluorescent in neutral aqueous buffer, with excitation and emission maxima at 293 and 376 nm, respectively. Binding to trypsin results in a blue shift of the emission peak to 362 nm, and 50-fold fluorescence enhancement, while binding
Nathan J Alves et al.
Biochemical and biophysical research communications, 457(3), 358-362 (2015-01-13)
The potent fibrinolytic enzyme, plasmin has numerous clinical applications for recannulizing vessels obstructed by thrombus. Despite its diminutive size, 91 kDa, success in the recombinant expression of this serine protease has been limited. For this reason, a truncated non-glycosylated plasmin
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