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Merck
CN

06880

4-氨基联苯胺 二盐酸盐

BioReagent, suitable for fluorescence, ≥99.0% (TLC)

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关于此项目

线性分子式:
H2NC6H4C(=NH)NH2·2HCl
化学文摘社编号:
分子量:
208.09
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
219-692-2
MDL number:
Beilstein/REAXYS Number:
3692927
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product line

BioReagent

assay

≥99.0% (TLC)

form

powder or crystals

mp

>300 °C (lit.)

fluorescence

λex >300 nm in H2O

suitability

suitable for fluorescence

storage temp.

2-8°C

InChI

1S/C7H9N3.2ClH/c8-6-3-1-5(2-4-6)7(9)10;;/h1-4H,8H2,(H3,9,10);2*1H

InChI key

GHEHNICLPWTXJC-UHFFFAOYSA-N

Analysis Note

Emmax: none

Other Notes

Competitive inhibitor of serine proteases; As a fluorescent probe for the active site of serine proteases


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Comparative studies on the inhibition of trypsin, plasmin, and thrombin by derivatives of benzylamine and benzamidine.
F Markwardt et al.
European journal of biochemistry, 6(4), 502-506 (1968-12-05)
STUDIES ON THE ACTIVE CENTER OF TRYPSIN. THE BINDING OF AMIDINES AND GUANIDINES AS MODELS OF THE SUBSTRATE SIDE CHAIN.
M MARES-GUIA et al.
The Journal of biological chemistry, 240, 1579-1585 (1965-04-01)
S A Evans et al.
The Journal of biological chemistry, 257(6), 3014-3017 (1982-03-25)
p-Aminobenzamidine is weakly fluorescent in neutral aqueous buffer, with excitation and emission maxima at 293 and 376 nm, respectively. Binding to trypsin results in a blue shift of the emission peak to 362 nm, and 50-fold fluorescence enhancement, while binding



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