09626
原卟啉 IX 二甲酯
~90% (HPLC)
别名:
二甲基-8,13-二乙烯基3,7,12,17四甲基-21H,23H-卟吩-2,18二丙, 间卟啉二甲酯
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关于此项目
经验公式（希尔记法）:
C36H38N4O4
化学文摘社编号:
分子量:
590.71
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
226-870-3
MDL number:
Beilstein/REAXYS Number:
381574
solubility
chloroform: soluble, diethyl ether: soluble, DMSO: soluble, THF: soluble, acetone: soluble, ethyl acetate: soluble, methanol: soluble
InChI key
XNCGCBXDDMJCKW-MFBGAUBSSA-N
InChI
1S/C36H38N4O4/c1-9-23-19(3)27-15-28-21(5)25(11-13-35(41)43-7)33(39-28)18-34-26(12-14-36(42)44-8)22(6)30(40-34)17-32-24(10-2)20(4)29(38-32)16-31(23)37-27/h9-10,15-18,38-39H,1-2,11-14H2,3-8H3/b27-15-,28-15-,29-16-,30-17-,31-16-,32-17-,33-18-,34-18-
assay
~90% (HPLC)
form
powder
mp
225-228 °C (lit.)
Quality Level
Gene Information
human ... TERT(7015)
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Application
原卟啉IX二甲基酯已被证明是人鼻咽癌的一种有效光敏剂。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Application of time-resolved fluorometry to the resolution of porphyrin-photoproduct mixtures.
P Valat et al.
Photochemistry and photobiology, 47(6), 787-790 (1988-06-01)
Vanaja Manivasager et al.
International journal of oncology, 29(4), 997-1002 (2006-09-12)
5-Aminolevulinic acid (5-ALA) and its esters have been under intense investigation to enhance the endogenous production of protoporphyrin IX (PpIX) in tumour cells for the purpose of photodynamic diagnosis. In this study we have investigated the use of exogenous PpIX
P P Tamburini et al.
Archives of biochemistry and biophysics, 245(2), 512-522 (1986-03-01)
The role of cytochrome b5 heme propionate groups in the functional interactions between cytochromes P-450 RLM5 and b5 has been investigated by comparing the capacity of RLM5 to interact with both native b5 and a b5 derivative in which the
S Adak et al.
The Biochemical journal, 334 ( Pt 1), 51-56 (1998-08-07)
The role of haem propionates in oxidative and reductive reactions catalysed by horseradish peroxidase (HRP) was studied after successful reconstitution of ferric protoporphyrin IX dimethyl ester (PPDME) into the apoperoxidase. The reconstituted enzyme oxidizes neither guaiacol (aromatic electron donor) nor
Arindam Sen et al.
Journal of controlled release : official journal of the Controlled Release Society, 82(2-3), 399-405 (2002-08-15)
Transdermal drug delivery is an attractive approach for either local or systemic treatment in medicine. In the last decade, different active transdermal delivery methods have been further investigated such as cationic liposomal delivery and electroporation-enhanced delivery. In light of gaining
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