09926
N-己酰基- DL -高丝氨酸内酯
≥97.0% (HPLC)
别名:
N-己酰基- DL -高丝氨酸内酯
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关于此项目
经验公式（希尔记法）:
C10H17NO3
化学文摘社编号:
分子量:
199.25
Beilstein:
1640340
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
方案
≥97.0% (HPLC)
表单
powder or crystals
技术
LC/MS: suitable
颜色
white to faint beige
mp
101-106 °C
储存温度
2-8°C
SMILES字符串
CCCCCC(=O)NC1CCOC1=O
CCCCCC(=O)NC1CCOC1=O
InChI
1S/C10H17NO3/c1-2-3-4-5-9(12)11-8-6-7-14-10(8)13/h8H,2-7H2,1H3,(H,11,12)
InChI key
ZJFKKPDLNLCPNP-UHFFFAOYSA-N
应用
在一个紫色色杆菌突变体中诱导紫花地丁的表达，该突变体通常不能产生高丝氨酸内酯。
生化/生理作用
N-己酰基-DL-高丝氨酸内酯是 N-酰基-高丝氨酸内酯家族的一员。N-酰基高丝氨酸内酯 (AHL) 调节革兰阴性细菌 、埃希杆菌 和沙门氏菌的基因表达，参与群体感应、细菌间的细胞间通讯。一些 AHL 是人类免疫细胞（如中性粒细胞）的强效化学引诱物。
群体感应信号生成
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Albert Soler et al.
International journal of environmental research and public health, 15(5) (2018-05-23)
Quorum sensing (QS) is a mechanism dependent on bacterial density. This coordinated process is mediated by the synthesis and the secretion of signal molecules, called autoinducers (AIs). N-acyl-homoserine lactones (AHLs) are the most common AIs that are used by Gram-negative
Daniel Wynn et al.
The Analyst, 143(19), 4774-4782 (2018-09-15)
There are an estimated 48 million cases of foodborne illness in the United States every year. In general, these illnesses are the result of unintentional contamination and improper food handling. Because bacterial contamination plays a major role in food spoilage
L Eberl
Systematic and applied microbiology, 22(4), 493-506 (2000-05-04)
The view of bacteria as unicellular organisms has strong roots in the tradition of culturing bacteria in liquid media. However, in nature microbial activity is mainly associated with surfaces where bacteria form highly structured and cooperative consortia which are commonly
Joanne Hothersall et al.
Applied microbiology and biotechnology, 90(3), 1017-1026 (2011-02-15)
Transcription of the 74 kb Pseudomonas fluorescens mupirocin [pseudomonic acid (PA)] biosynthesis cluster depends on quorum sensing-dependent regulation via the LuxI/LuxR homologues MupI/MupR. To facilitate analysis of novel PAs from pathway mutants, we investigated factors that affect mup gene expression.
Robert Czajkowski et al.
Acta biochimica Polonica, 56(1), 1-16 (2009-03-17)
Many Gram-positive and Gram-negative bacteria communicate using small diffusible signal molecules called autoinducers. This process, known as quorum sensing (QS), links cell density to the expression of genes as diverse as those associated with virulence factors production of plant and
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