biological source
human plasma
assay
≥90% (GE)
form
lyophilized solid
solubility
H2O: 1 mg/mL, clear, colorless
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... APOA1(335)
General description
Apolipoprotein A-I (apoA-I) is the chief protein component of high density lipoproteins (HDL) and a major determinant of HDL structure, composition, and stability. It is an exchangeable apolipoprotein and plays pivotal role in the metabolism of cholesterol.
Application
Apolipoprotein A-I (apoA-I) was used for protecting the heart against vascular disease, it also protects other vascular beds and organs. It was protective against atherosclerosis through its ability to intervene in reverse cholesterol transport.
Biochem/physiol Actions
High-density lipoproteins are antiatherogenic and cardioprotective by facilitating reverse cholesterol transport (RCT). Some strategies for elevating apolipoprotein A-I levels are studied as therapies for atherosclerosis.
Preparation Note
lyophilized from 0.01 M ammonium hydrogen carbonate
Other Notes
A principal protein component of high-density lipoproteins. Protein - lipid interactions
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存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable