CD20 (SP32) Rabbit Monoclonal Antibody

Anti-CD20 (pan B-cell) reacts with a membrane antigen that is present in B-cells as this epitope is acquired late in the pre-B-cell stage of maturation and remains on cells throughout most of the differentiation process, although it is lost at the plasma cell stage. This antibody recognizes Reed-Sternberg cells, predominant in classic Hodgkin′s disease, in approximately 20% of cases, and approximately half of lymphoblastic lymphoma/leukemias. Since no staining of histiocytes or plasma cells has been observed and CD20 has rarely been detected in T-cell malignancies, it is a dependable marker of B-cell lymphomas. Anti-CD20 does not cross-react with non-hematopoetic neoplasms.

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

CD20 Positive Control Slides, Product No. 120S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

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