12247
橄榄苦苷
≥98.0%
别名:
(2S,3E,4S)-3-亚乙基-2-（β-D-葡吡喃糖氧基）-3,4-二氢-5-（甲氧羰基）-2 H-吡喃-4-乙酸 2-（3,4-二羟苯基）乙酯
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关于此项目
经验公式（希尔记法）:
C25H32O13
化学文摘社编号:
分子量:
540.51
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
251-129-6
MDL number:
Quality Segment
assay
≥98.0%
impurities
≤5.0% water
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
SMILES string
COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OCCc3ccc(O)c(O)c3
InChI
1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1
InChI key
RFWGABANNQMHMZ-ZCHJGGQASA-N
General description
橄榄苦苷是橄榄叶提取物中发现的主要次生代谢产物。它是一种环烯醚萜多酚，其结构由烯烯酸与羟酪醇的糖基化酯组成。
Application
橄榄苦苷已被用于：
- 作为一种抗炎和抗氧化剂，在高脂饮食(HFD)喂养的小鼠肝脏脂肪变性
- 评估雄性小鼠生殖功能的保护作用及抗氧化特性
- 研究其对细菌（大肠杆菌）ATP合酶的抑制作用
- 作为纤溶酶原激活物抑制剂-1 (PAI-1)的抑制剂，检测其对乳腺癌细胞增殖的影响
Biochem/physiol Actions
橄榄苦苷具有抗癌、抗微生物、抗病毒、抗缺血和降血脂活性。对皮肤起保护作用，有助于抗衰老。橄榄苦苷还有抗血小板聚集、降压、抗风湿、解热、利尿和血管舒张作用。降低患冠状动脉疾病的风险。橄榄苦苷能促进分泌去甲肾上腺素和肾上腺素。
Packaging
无底玻璃瓶。内容物在插入的熔锥内。
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Oleuropein overrides liver damage in steatotic mice
Santini SJ, et al.,
Journal of functional foods, 65, 103756-103756 (2020)
Amon Amini et al.
International journal of biological macromolecules, 101, 153-164 (2017-03-23)
The naturally occurring olive phenolics tyrosol, hydroxytyrosol, dihydroxyphenylglycol (DHPG), and oleuropein are known to have antioxidant, antitumor, and antibacterial properties. In the current study, we examined whether the antimicrobial properties of tyrosol, hydroxytyrosol, DHPG, and oleuropein were linked to the
Carla Marchetti et al.
Evidence-based complementary and alternative medicine : eCAM, 2015, 908493-908493 (2015-12-23)
Malignant mesothelioma is a poor prognosis cancer in urgent need of alternative therapies. Oleuropein, the major phenolic of olive tree (Olea europaea L.), is believed to have therapeutic potentials for various diseases, including tumors. We obtained an oleuropein-enriched fraction, consisting
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 12247-50MG | 04061833248829 |
| 12247-10MG | 04061838721273 |