登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
C23H19N2O5Na
化学文摘社编号:
分子量:
444.41
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
255-530-7
MDL number:
InChI key
HEJYVLSWQWPKPQ-BDQAORGHSA-M
InChI
1S/C23H20N2O5.Na/c26-19-12-6-15(7-13-19)14-20(25-21(27)16-4-2-1-3-5-16)22(28)24-18-10-8-17(9-11-18)23(29)30;/h1-13,20,26H,14H2,(H,24,28)(H,25,27)(H,29,30);/q;+1/p-1/t20-;/m0./s1
SMILES string
[Na+].Oc1ccc(C[C@H](NC(=O)c2ccccc2)C(=O)Nc3ccc(cc3)C([O-])=O)cc1
assay
≥98.0% (sum of enantiomers, HPLC)
form
powder or crystals
optical activity
[α]20/D +45±2°, c = 1% in DMF/H2O 1:1
quality
lyophilized
mp
~210 °C (dec.)
solubility
water: 0.25 g/5mL, clear to slightly hazy
storage temp.
2-8°C
General description
N-Benzoyl-L-tyrosine p-amidobenzoic acid acts as a substrate for peptide hydrolases present in the human small intestinal mucosa. Its degradation to p-aminobenzoic acid helps to assess the pancreatic and renal functionality.
Other Notes
Hydrolysis of benzol-tyrosyl-p-aminobenzoic acid by a human intestinal microvillar peptidase; Substrate for the assay of chymotrypsin in crude biological materials.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
A method for the assay of chymotrypsin in crude biological materials.
A R Imondi et al.
Analytical biochemistry, 54(1), 199-204 (1973-07-01)
C Lang et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 18(9), 551-555 (1980-09-01)
The oral pancreatic function test with N-benzoyl-L-tyrosyl-p-aminobenzoic acid was performed on 24 healthy test subjects, and its toxicity was examined. Eight patients with restricted renal function and known renal disease were also investigated. The pancreatic function test and the same
E E Sterchi et al.
Clinical science (London, England : 1979), 62(5), 557-560 (1982-05-01)
1. Hydrolysis of N-benzoyl-L-tyrosyl-p-aminobenzoic acid (PABA-peptide) has been measured in soluble and particulate fractions of human small intestinal mucosa. 2. Both soluble and particulate fractions contained enzymic activity capable of splitting the PABA-peptide. In the particulate fractions this activity increased
P.W. Pemberton et al.
Biochemical Society Transactions, 13, 175-175 (1985)
商品
Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持