131R-2
CD31 (EP78) Rabbit Monoclonal Primary Antibody
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
EP78, monoclonal
Application:
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species reactivity:
human
Citations:
4
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
EP78, monoclonal
description
(For In Vitro Diagnostic Use in Select Regions (See Chart))
form
buffered aqueous solution
species reactivity
human
packaging
bottle of 1.0 mL predilute (131R-27)
bottle of 7.0 mL predilute (131R-28)
vial of 0.1 mL concentrate (131R-24)
vial of 0.5 mL concentrate (131R-25)
vial of 1.0 mL concentrate (131R-26)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... PECAM1(5175)
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Endothelial cells also express this marker; therefore, antibodies to CD31 have been used as a tool to identify the vascular origin of neoplasms.1-3 Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells.4 Staining of nonvascular tumors (excluding hematopoietic neoplasms) has not been observed.
Other Notes
CD31 Positive Control Slides, Product No. 131S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
B R De Young et al.
American journal of clinical pathology, 110(3), 374-377 (1998-09-05)
CD31 is a specific and sensitive marker of endothelial differentiation. Previous reports have described its immunoreactivity in large series of soft tissue neoplasms, as well as its comparison with other available and commonly used endothelial markers. CD31 reactivity in carcinomas
J U Alles et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 34(2), 209-214 (1986-02-01)
A new monoclonal antibody (moab BW 200) of IgG3 kappa-isotype was generated which recognizes an epitope located on an antigen molecule restricted to human neoplastic and non-neoplastic endothelial cells. The molecular weight of the antigen was determined using immunoprecipitation analysis
F Alexander-Sefre et al.
Journal of clinical pathology, 56(10), 786-788 (2003-09-30)
Lymphovascular space invasion (LVSI) is an important step in the complex process of tumour metastasis. Various methods have been used in the past to improve the histological detection of LVSI. To develop a sensitive immunohistochemical method for the detection of
D V Parums et al.
Journal of clinical pathology, 43(9), 752-757 (1990-09-01)
A new monoclonal antibody, JC70, raised against a membrane preparation from a spleen affected by hairy cell leukaemia, recognises a membrane bound glycoprotein identical with that of the CD31 group of monoclonal antibodies. The antibody stains a fixation resistant epitope
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