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Merck
CN

134M-1

CD34 (QBEnd/10) Mouse Monoclonal Antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203

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biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

QBEnd/10, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (134M-14)
vial of 0.5 mL concentrate (134M-15)
bottle of 1.0 mL predilute (134M-17)
vial of 1.0 mL concentrate (134M-16)
bottle of 7.0 mL predilute (134M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG1

control

placenta, tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Quality Level

100
500

Gene Information

human ... CD34(947)

相关类别

Analysis Note


IVD
IVD
IVD
RUO

General description

CD34 is a cell surface glycophosphoprotein expressed on human hematopoietic progenitor cells and can be used for identifying blast cells. CD34 is a marker for vascular endothelial cells and has been shown in the literature to be highly sensitive to angiosarcomas and Kaposi’s sarcomas. In addition, CD34 is expressed in soft tissue tumors such as gastrointestinal stromal tumors (GIST).

Other Notes

CD34 Positive Control Slides, Product No. 134S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000477583
0000477583
0000477609
0000477594
0000477608

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E A Sankey et al.
The Journal of pathology, 161(3), 267-271 (1990-07-01)
Kaposi's sarcomas are seen more commonly in routine histopathology laboratories since the advent of the more widespread and aggressive variant of the disease associated with HIV infection. Distinguishing nodular lesions from other spindle cell and vascular tumours can sometimes be
Goran Torlakovic et al.
Archives of pathology & laboratory medicine, 126(7), 823-828 (2002-06-29)
The immunohistochemical detection of CD34 protein using QBEND10 antibody in bone marrow trephine biopsies was shown recently to be a precise method for quantitation of blasts and a possibly useful approach in diagnosis and classification of myelodysplastic syndrome. To evaluate
Joanna Kiśluk et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 22(1), 33-39 (2013-03-08)
Gastrointestinal stromal tumors (GISTs) are the most common cancers of mesenchymal origin in the abdomen. An approximately 95% of GISTs show positive expression of the membrane receptor c-kit (CD117 antigen), which currently constitutes the basis for histopathological diagnosis if this
P Ramani et al.
Histopathology, 17(3), 237-242 (1990-09-01)
The immunoreactivity of a new monoclonal antibody to endothelium. QBEND/10, in formalin-fixed, paraffin-embedded sections from a variety of vascular and lymphatic tumours is described and compared to that of two other endothelial markers, von Willebrand factor and Ulex europaeus agglutinin

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Immunohistochemistry Applications in Gastrointestinal Cancer

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

胃肠道癌症中的免疫组织化学应用

结直肠癌是男性和女性中第三大常见癌症。预计2016年将发生136,000例结直肠癌。

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