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Merck
CN

134R-1

CD34 (EP88) Rabbit Monoclonal Primary Antibody

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UNSPSC Code:
12352203

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biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP88, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (134R-14)
vial of 0.1 mL concentrate Research Use Only (134R-14-RUO)
vial of 0.5 mL concentrate (134R-15)
vial of 1.0 mL concentrate (134R-16)
vial of 1.0 mL concentrate Research Use Only (134R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (134R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (134R-17)
vial of 7.0 mL pre-dilute ready-to-use (134R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (134R-18-RUO)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

isotype

IgG

control

placenta, tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Quality Level

100
500

Gene Information

human ... CD34(947)

相关类别

Analysis Note


IVD
IVD
IVD
RUO

General description

CD34 is a cell surface glycophosphoprotein expressed on human hematopoietic progenitor cells, vascular endothelial cells, and embryonic fibroblasts. The exact function of CD34 has not yet been determined, though studies have found it may enhance proliferation and block differentiation of stem or progenitor cells, and promote lymphocyte adhesion to vascular endothelium in lymphoid tissues. CD34 expression has also been observed in some gastrointestinal stromal tumors (GIST).

Other Notes

CD34 Positive Control Slides, Product No. 134S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Note: This IFU may not apply to your specific product lot.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000519811
0000519811
0000413971
0000413971
0000409023

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Julie S Nielsen et al.
Journal of cell science, 121(Pt 22), 3683-3692 (2008-11-07)
For almost 30 years, the cell-surface protein CD34 has been widely used as a marker to assist in the identification and Summary isolation of hematopoietic stem cells (HSCs) and progenitors in preparation for bone-marrow transplantation. In addition, it has increasingly
Goran Torlakovic et al.
Archives of pathology & laboratory medicine, 126(7), 823-828 (2002-06-29)
The immunohistochemical detection of CD34 protein using QBEND10 antibody in bone marrow trephine biopsies was shown recently to be a precise method for quantitation of blasts and a possibly useful approach in diagnosis and classification of myelodysplastic syndrome. To evaluate
Joanna Kiśluk et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 22(1), 33-39 (2013-03-08)
Gastrointestinal stromal tumors (GISTs) are the most common cancers of mesenchymal origin in the abdomen. An approximately 95% of GISTs show positive expression of the membrane receptor c-kit (CD117 antigen), which currently constitutes the basis for histopathological diagnosis if this

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