跳转至内容
Merck
CN

135R-1

CD35 (EP197) Rabbit Monoclonal Primary Antibody

别名:

C3-binding protein, C3BR, C3b/C4b receptor, C4BR, CD35 antigen, CR1, Complement Receptor 1, Complement component (3b/4b) receptor 1 (Knops blood group), Knops blood group antigen

登录 查看组织和合同定价。

选择尺寸

关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
EP197, monoclonal
Application:
IHC (p)
Citations:
12

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP197, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (135R-14), vial of 0.1 mL concentrate Research Use Only (135R-14-RUO), vial of 0.5 mL concentrate (135R-15), vial of 1.0 mL concentrate (135R-16), vial of 1.0 mL concentrate Research Use Only (135R-16-RUO), vial of 1.0 mL pre-dilute Research Use Only (135R-17-RUO), vial of 1.0 mL predilute ready-to-use (135R-17), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (135R-18-RUO), vial of 7.0 mL predilute ready-to-use (135R-18)

manufacturer/tradename

Cell Marque®

concentration

0.1-5.0 μg/mL (predilute), 2.5-125 μg/mL (concentrate)

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

isotype

IgG

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Quality Level

100, 500

Gene Information

human ... CR1(1378)

相关类别

General description

CD35 (complement receptor 1) is a cell membrane-bound, monomeric glycoprotein found on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Download the latest released IFU
Note: This IFU may not apply to your specific product lot.

Analysis Note

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Other Notes

CD35 Positive Control Slides, Product No. 135S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

未找到合适的产品？  

试试我们的产品选型工具.

存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000532149
0000532149
0000509534
0000509534
0000509477

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Germinal centre-like versus undifferentiated stromal immunophenotypes in follicular lymphoma.
Chang KC, Huang X, Medeiros LJ, et al.
The Journal of Pathology, 201(3), 404-412 (2003)
Immunohistochemical recognition of human follicular dendritic cell (FDCs) in routinely processed paraffin section.
Kunihikom, M., et al.
The Journal of Histochemistry and Cytochemistry, 50, 1475-1486 (2002)
Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases.
Pileri SA, Grogan TM, Harris NL, et al.
Histopathology, 41(1), 1-29 (2002)
Inflammatory pseudotumor-like follicular dendritic cell tumor: a distinctive low-grade malignant intra-abdominal neoplasm with consistent Epstein-Barr virus association.
Cheuk W, Chan JK, Shek TW, et al.
American Journal of Surgical Pathology, 25(6), 721-731 (2001)
Mediastinal mixed dendritic cell sarcoma with hybrid features.
Dillon KM, Hill CM, Cameron CH, et al.
Journal of Clinical Pathology, 55(10), 791-794 (2002)
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持